Role of corticosterone on sleep homeostasis induced by REM sleep deprivation in rats. [PDF]
PLoS ONE, 2013 Sleep is regulated by humoral and homeostatic processes. If on one hand chronic elevation of stress hormones impair sleep, on the other hand, rapid eye movement (REM) sleep deprivation induces elevation of glucocorticoids and time of REM sleep during the
Ricardo Borges Machado +2 more
doaj +9 more sources
Molecular Mechanisms of REM Sleep [PDF]
Frontiers in Neuroscience, 2020 Rapid-eye movement (REM) sleep is a paradoxical sleep state characterized by brain activity similar to wakefulness, rapid-eye-movement, and lack of muscle tone.
Rikuhiro G. Yamada +2 more
doaj +4 more sources
Assessing REM Sleep as a Biomarker for Depression Using Consumer Wearables [PDF]
DiagnosticsBackground: Rapid-eye-movement (REM) sleep disinhibition—shorter REM latency and a larger nightly REM fraction—is a well-described laboratory correlate of major depression.
Roland Stretea +6 more
doaj +2 more sources
Isolated Rem Sleep Behavior Disorder: A Model to Assess the Overnight Habituation of Emotional Reactivity [PDF]
Clocks & Sleep(1) Background: Phasic events in rapid eye movement (REM) sleep are a core feature of isolated REM behavior disorder (iRBD), which is often associated with emotion dysregulation.
Caterina Leitner +5 more
doaj +2 more sources
An Asymmetrical Hypothesis for the NREM-REM Sleep Alternation—What Is the NREM-REM Cycle?
Frontiers in Neuroscience, 2021 Since the discovery of rapid eye movement (REM) sleep (Aserinsky and Kleitman, 1953), sleep has been described as a succession of cycles of non-REM (NREM) and REM sleep episodes.
Olivier Le Bon
doaj +1 more source
A probabilistic model for the ultradian timing of REM sleep in mice.
PLoS Computational Biology, 2021 A salient feature of mammalian sleep is the alternation between rapid eye movement (REM) and non-REM (NREM) sleep. However, how these two sleep stages influence each other and thereby regulate the timing of REM sleep episodes is still largely unresolved.
Sung-Ho Park +6 more
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REM sleep deprivation during 5 hours leads to an immediate REM sleep rebound and to suppression of non-REM sleep intensity [PDF]
, 1990 Nine healthy male subjects were deprived of REM sleep during the first 5 h after sleep onset. Afterwards recovery sleep was undisturbed. During the deprivation period the non-REM EEG power spectrum was reduced when compared to baseline for the ...
Achermann +22 more
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Frontiers in Cardiovascular Medicine, 2022 ObjectivesRapid eye movement (REM) sleep is closely related to all-cause mortality. The aim of this study is to explore the role of REM sleep on the incident heart failure (HF).MethodsWe selected 4490 participants (2480 women and 2010 men; mean age, 63.2
Binbin Zhao +11 more
doaj +1 more source
Methods for REM Sleep Density Analysis: A Scoping Review
Clocks & Sleep, 2023 Rapid eye movements (REM) sleep density is the parameter proposed to explain the variability in the amount of eye movements during REM sleep. Alterations in REM sleep density have been proposed as a screening criterion for individuals with depression and
Tamires Tiemi Kishi +5 more
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A cluster of mesopontine GABAergic neurons suppresses REM sleep and curbs cataplexy
Cell Discovery, 2022 Physiological rapid eye movement (REM) sleep termination is vital for initiating non-REM (NREM) sleep or arousal, whereas the suppression of excessive REM sleep is promising in treating narcolepsy.
Ze-Ka Chen +17 more
doaj +1 more source