Results 51 to 60 of about 237,453 (287)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Study on Remaining Oil Distribution after Polymer Injection

, 2010
The recovery efficiency by polymer flooding is 10% higher than that of water flooding for main reservoirs in Daqing Oil Field, and yearly oil production rate by polymer injection has continuously reached over 10 million tons for 8 years.
Han Peihui, Kaoping Song, Jianguang wei, Jiecheng Cheng   +3 more
core   +1 more source

Integrated Rock Physics-Based Interpretation of Time-Lapse Seismic Data for Residual Oil Detection in Offshore Waterflooded Reservoirs

Journal of Marine Science and Engineering
Accurate characterization of fluid distribution in offshore waterflooded oilfields has been challenging due to complex heterogeneity and the limitations of traditional interpretation tools, which often cannot integrate multi-scale datasets such as core ...
Haoyuan Li, Xuri Huang, Sheng Yang, Xiaoqing Cui, Yibin Li, Ran Yang   +5 more
doaj   +1 more source

Experiments on water flooding in fractured-vuggy cells in fractured-vuggy reservoirs

Petroleum Exploration and Development, 2014
Based on the theory of scaling criteria, a physical experimental model of fractured-vuggy cell which meets the geometric similarity, kinematic similarity, dynamic similarity and characteristic parameters similarity was designed.
Jing WANG, Huiqing LIU, Zhengfu NING, Hongling ZHANG, Cheng HONG   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Influence of micro displacement effect of permeability on water flooding and the direction of tapping potential of fluvial reservoir

Youqicang pingjia yu kaifa, 2021
The geological conditions of marine fluvial sedimentary reservoir are very complex.In the process of water flooding development,the remaining oil distribution is dispersed and it is difficult to develop due to different water absorption in the same ...
CHEN Ke, ZHANG Xudong, HE Wei, YIN Chao, TANG Lei, ZHANG Hu, YE Zhongbin   +6 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Pore-Scale Simulation of Particle Flooding for Enhancing Oil Recovery

Energies, 2021
The particles, water and oil three-phase flow behaviors at the pore scale is significant to clarify the dynamic mechanism in the particle flooding process.
Xiangbin Liu, Le Wang, Jun Wang, Junwei Su   +3 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source