Results 61 to 70 of about 419,717 (299)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Hybrid Prognostic Methodology and its Application to Well-Controlled Engineering Systems [PDF]

, 2015
This thesis presents a novel hybrid prognostic methodology, integrating physics-based and data-driven prognostic models, to enhance the prognostic accuracy, robustness, and applicability.
Eker, Ömer Faruk
core  

A semi-supervised approach with monotonic constraints for improved remaining useful life estimation [PDF]

, 2022
Remaining useful life is of great value in the industry and is a key component of Prognostics and Health Management (PHM) in the context of the Predictive Maintenance (PdM) strategy.
Ompusunggu, Agusmian Partogi, Vandermoortele, Nathan, Colin Soete, Agusmian Partogi Ompusunggu, Van Hoecke, Sofie, Dirk Deschrijver, Pieter Moens, Nieves Avendano, Diego, Soete, Colin, Nathan Vandermoortele, Deschrijver, Dirk, Diego Nieves Avendano, Sofie Van Hoecke, Moens, Pieter, Vandemoortele, Nathan   +14 more
core   +1 more source

Life extension of wind turbine drivetrains by means of SCADA data: Case study of generator bearings in an onshore wind farm

Results in Engineering
Accurate predictions for remaining useful life (RUL) of wind turbine drivetrains are crucial in reducing downtime, optimising maintenance strategies, extending operational life and improving costs.
Kelly Tartt, Abbas Mehrad Kazemi-Amiri, Amir R. Nejad, James Carroll, Alasdair McDonald   +4 more
doaj   +1 more source

Remaining Useful Life Estimation in Prognostics Using Deep Reinforcement Learning

IEEE Access, 2023
In modern industrial systems, condition-based maintenance (CBM) has been wildly adopted as an efficient maintenance strategy. Prognostics, as a key enabler of CBM, involves the kernel task of estimating the remaining useful life (RUL) for engineered ...
Qiankun Hu, Yongping Zhao, Yuqiang Wang, Pei Peng, Lihua Ren   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Predicting the Remaining Useful Life of Supercapacitors under Different Operating Conditions

Energies
With the rapid development of the new energy industry, supercapacitors have become key devices in the field of energy storage. To forecast the remaining useful life (RUL) of supercapacitors, we introduce a new technology that integrates variational mode ...
Guangheng Qi, Ning Ma, Kai Wang
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Prognostics for electronics components of avionics - NASA IGBT accelerated ageing case study [PDF]

, 2013
Insulate gate bipolar transistors (IGBTs) are widely used in electric vehicles, railway locomotive and new generation aircrafts, due to the IGBTs have advantages in small conduction resistance and small drive current.
Xie, Yuan'an
core