Results 71 to 80 of about 419,717 (299)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Data-Driven Machine Learning Methods for Remaining Useful Life Prediction
I will present my work exploring machine learning solutions for remaining useful life prediction for physical devices. In my work, I predict remaining useful life for hard-disk drives and aircraft engines.
Coursey, Austin
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Digital Twin and Data-Driven Remaining Useful Life Prediction of Gearbox
Traditional approaches for predicting the remaining useful life (RUL) of gearboxes often face challenges in integrating physical and virtual data, leading to reduced prediction accuracy and an increased risk of system failure.
Quanbo Lu, Mei Li, Xiaojuan Huang
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Remaining useful life prediction based on an integrated neural network
Unexpected failures and unscheduled maintenance activities of mechanical systems might incur considerable waste of resources and high investment costs. Thus, in recent years, prognostics and health management (PHM) has received a lot of attention because
Yong-feng ZHANG, Zhi-qiang LU
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Remaining useful life prediction: from statistical modeling to federated approach
Smart manufacturing is getting increasingly popular in different areas, including aircraft systems, uninterruptible power supply systems, hydraulic systems, etc. Meanwhile, the capability of intelligent machines doing edge computing is growing rapidly.
Gan, Xin
core
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source

