Results 71 to 80 of about 530,506 (256)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Trend-Fluctuation Correlated Attention Unit for Remaining Useful Life Prediction
IEEE AccessHealth indicators (HIs) are measures that consolidate complex machinery characteristics into a single dimension and have been extensively studied for predicting the remaining useful life (RUL).
Hanbyeol Park +3 more
doaj +1 more source
Predictive Maintenance on the Machining Process and Machine Tool [PDF]
, 2019 This paper presents the process required to implement a data driven Predictive Maintenance (PdM) not only in the machine decision making, but also in data acquisition and processing.
Box +13 more
core +2 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Applying the General Path Model to Estimation of Remaining Useful Life [PDF]
, 2011 The ultimate goal of most prognostic systems is accurate prediction of the remaining useful life of individual systems or components based on their use and performance.
J. Wesley Hines, Jamie Coble
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A Discussion on Uncertainty Representation and Interpretation in Model-Based Prognostics Algorithms based on Kalman Filter Estimation Applied to Prognostics of Electronics Components [PDF]
, 2012 This article discusses several aspects of uncertainty representation and management for model-based prognostics methodologies based on our experience with Kalman Filters when applied to prognostics for electronics components.
Celaya, Jose R. +2 more
core +1 more source
A fuzzy expectation maximization based method for estimating the parameters of a multi-state degradation model from imprecise maintenance outcomes [PDF]
, 2017 Multi-State (MS) reliability models are used in practice to describe the evolution of degradation in industrial components and systems. To estimate the MS model parameters, we propose a method based on the Fuzzy Expectation-Maximization (FEM) algorithm ...
Cannarile, F. +3 more
core +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source