Results 71 to 80 of about 10,623,511 (284)

Estimation of the remaining useful life of hydro generators [PDF]

, 2021
O monitoramento da condição dos geradores é muito desejável para uma operação confiável de uma usina hidrelétrica. As atividades de manutenção podem ser programadas para evitar falhas inesperadas que podem levar a meses ou anos de máquinas paradas sem ...
BERNARDES JUNIOR, José Vitor
core   +1 more source

Rolling Bearing Remaining Useful Life Prediction Based on CNN-VAE-MBiLSTM

Sensors
Ensuring precise prediction of the remaining useful life (RUL) for bearings in rolling machinery is crucial for preventing sudden machine failures and optimizing equipment maintenance strategies.
Lei Yang, Yibo Jiang, Kang Zeng, Tao Peng   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Data-Driven Machine Learning Methods for Remaining Useful Life Prediction

, 2022
I will present my work exploring machine learning solutions for remaining useful life prediction for physical devices. In my work, I predict remaining useful life for hard-disk drives and aircraft engines.
Coursey, Austin
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Trend-Fluctuation Correlated Attention Unit for Remaining Useful Life Prediction

IEEE Access
Health indicators (HIs) are measures that consolidate complex machinery characteristics into a single dimension and have been extensively studied for predicting the remaining useful life (RUL).
Hanbyeol Park, Sunghyun Sim, Yunkyung Park, Hyerim Bae   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Prognostic modelling options for remaining useful life estimation by industry

, 2011
Over recent years a significant amount of research has been undertaken to develop prognostic models that can be used to predict the remaining useful life of engineering assets.
M. Hodkiewicz, J.Z. Sikorska, Hodkiewicz, Melinda, L. Ma, Ma, Lin, Sikorska, Joanna   +5 more
core   +1 more source