Results 81 to 90 of about 10,623,511 (284)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Machine condition prognosis based on regression trees and one-step-ahead prediction [PDF]

, 2008
Predicting the degradation of working conditions of machinery and trending of fault propagation before they reach the alarm or failure threshold is extremely important in industry to fully utilize the machine production capacity.
Yang, Bo-Suk, Tan, Andy Chit Chiow, Tran, Van, Tran, Van Tung, Oh, Myung-Suck, Tan, Andy   +5 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Prediction of the remaining useful life of a milling machine using machine learning

MethodsX
The cutting tool is a key component of the milling machine that decides productivity. Hence, an adequate predictive maintenance (PdM) strategy for the cutting tools becomes necessary. This research seeks to develop a smart maintenance web application that utilizes Machine Learning (ML) supervised models to predict the Remaining Useful Life (RUL) for ...
Abbas Al-Refaie, Majd Al-atrash, Natalija Lepkova   +2 more
openaire   +3 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Remaining useful life prediction: from statistical modeling to federated approach

, 2022
Smart manufacturing is getting increasingly popular in different areas, including aircraft systems, uninterruptible power supply systems, hydraulic systems, etc. Meanwhile, the capability of intelligent machines doing edge computing is growing rapidly.
Gan, Xin
core  

Mixup Domain Adaptations for Dynamic Remaining Useful Life Predictions

CoRR
accepted for publication in Knowledge-based ...
Muhammad Tanzil Furqon, Mahardhika Pratama, Lin Liu 0003, Habibullah Habibullah, Kutluyil Dogancay   +4 more
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Lithium-ion batteries Remaining Useful Life Prediction Method Considering Recovery Phenomenon

International Journal of Electrochemical Science, 2019
Estimation of lithium battery remaining useful life (RUL) is the key to lithium battery health management. In the process of intermittent discharging lithium batteries, the recovery phenomenon will have a relatively large impact on the life of lithium ...
Zhenyu Zhang, Dongxu Shen, Zhen Peng, Yong Guan, Huimei Yuan, Lifeng Wu   +5 more
doaj   +1 more source