Results 41 to 50 of about 796,593 (383)
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Former cod fisherman and historian Ted Ames of Stonington, Maine, says he heard about an old salt who "hauled in 25 tons in 20 minutes after steaming to a favorite fishing spot. ...
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Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
'Wellcome History' is an easy and regular channel of communication between all Wellcome historians.
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I published an interview of Leo Breiman in Statistical Science [Olshen (2001)], and also the solution to a problem concerning almost sure convergence of binary tree-structured estimators in regression [Olshen (2007)].
Olshen, Richard A.
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Processing speed, executive function, and age differences in remembering and knowing. [PDF]
A group of young (n = 52, M = 23.27 years) and old (n = 52, M = 68.62 years) adults studied two lists of semantically unrelated nouns. For one list a time of 2 s was allowed for encoding, and for the other, 5 s.
Bunce, D, Macready, A
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Remembering Events and Remembering Looks [PDF]
I describe and discuss one particular dimension of disagreement in the philosophical literature on episodic memory. One way of putting the disagreement is in terms of the question as to whether or not there is a difference in kind between remembering seeing x and remembering what x looks like.
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Wasssily Hoeffding's terminal illness and untimely death in 1991 put an end to efforts that were made to interview him for Statistical Science. An account of his scientific work is given in Fisher and Sen [The Collected Works of Wassily Hoeffding (1994 ...
Fisher, Nicholas I., van Zwet, Willem R.
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