Results 31 to 40 of about 120,055 (283)
Designing for Collective Remembering [PDF]
, 2006 This paper outlines the rationale for the workshop topic and offers an overview of its ...
Dix, Alan, Sas, Corina
core +5 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Sostare nel ricordo: esercizi di topofilia e progetto
Ri-vista: Ricerche per la Progettazione del Paesaggio, 2022 The essay is about the aesthetic experience of staying and about the relationship we establish with the landscape when we stop walking. Right at that moment, our body generates a new relationship with the place, merging more and more into the ...
Marco Cillis
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Remembering Peasants takes an expert deep dive into a vanishing world. Professor Patrick Joyce aligns his academic expertise with a personal testimony. Most of us are only one or two generations away from our peasant ancestry.
O'Connor, F.
core +3 more sources
Framing Deaths, Embracing Lives: Alan M. Clark’s Jack the Ripper Victims Series
HumanitiesJack the Ripper fictions tend to be realist in mode, making frequent use of the Victorian press and archives to depict the 1888 murders. At the same time, they marginalise and exploit the victims, defining them as silent testimonies to the power of the ...
Lucyna Krawczyk-Żywko
doaj +1 more source
Remembering Reverend Professor Bolesław Przybyszewski (1908-2001)
Folia Historica Cracoviensia, 2002 A recollection of Rev. prof. Bolesław Przybyszewski.
Stanisław Piech
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source