Results 61 to 70 of about 538,157 (308)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Epilogue [PDF]

open access: yes, 2017
Authors' accepted manuscript of a chapter from: Declan Marmion & Salvador Ryan (eds), Remembering the Reformation : Martin Luther and Catholic ...
Bagchi, David
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Framing Deaths, Embracing Lives: Alan M. Clark’s Jack the Ripper Victims Series

open access: yesHumanities
Jack the Ripper fictions tend to be realist in mode, making frequent use of the Victorian press and archives to depict the 1888 murders. At the same time, they marginalise and exploit the victims, defining them as silent testimonies to the power of the ...
Lucyna Krawczyk-Żywko
doaj   +1 more source

Essay: Remembering Jorge Leon Trujillo (1948-2017)

open access: yesÍconos, 2018
Essay Remembering Jorge Leon Trujillo (1948-2017)
Hernán Ibarra
doaj   +1 more source

Penggunaan Mnemonik Alkitab Model Paralel Untuk Mengingat Ayat-Ayat Alkitab

open access: yesDidache, 2020
Mnemonics are related to remembering and recalling, and have been used for thousands of years. Mnemonic strategies have been used in various fields both psychology and medical. In this case the writer wants to examine the use of mnemonics in remembering
Tjie Fu Sien
doaj   +1 more source

An Essay on the Ontological Foundations and Psychological Realization of Forgetting [PDF]

open access: yes, 2019
I argue that appreciation of the phenomenon of forgetting requires serious attention to its origins and place in nature. This, in turn, necessitates metaphysical inquiry as well as empirical backing – a combination likely to be eschewed by psychological
Klein, Stan
core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Wandering in Pakistan: The Paradoxical World of the Marginalized in Nadeem Aslam’s The Golden Legend (2017)

open access: yesJournal of Language and Literature
This study explores the idea of place in Nadeem Aslam’s The Golden Legend (2017) to frame the identity crisis befalling the Christian community in Pakistan as a mirror of the similar experiences of marginalized groups in Britain.
Firda Khoirunnisa   +2 more
doaj   +1 more source

Unsuccessful remembering: A challenge for the relational view of memory [PDF]

open access: yes
This paper explores the relationship between a prominent version of the relational view of memory and recent work on forms of unsuccessful remembering or memory errors. I argue that unsuccessful remembering poses an important challenge for the relational
Sant’Anna, André
core  

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