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Safety of Remimazolam in Vulnerable Populations
Drug Design, Development and TherapyVulnerable populations require careful consideration in drug selection due to their unique physiological conditions. Remimazolam, an innovative ultra-short-acting benzodiazepine, presents several advantages, including rapid onset, brief duration of action, and high predictability.
Jia-Yi Ge +3 more
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脊髄後角ニューロンの抑制性伝達に対するレミマゾラムの作用 [PDF]
新潟大学Niigata University博士（医学）Remimazolam is an ultra-short benzodiazepine that acts on the benzodiazepine site of γ-aminobutyric acid (GABA) receptors in the brain and induces sedation. Although GABA receptors are found localized in the spinal dorsal horn,
Hoshino, Rintaro, 星野, 林太郎
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Remimazolam use for awake craniotomy [PDF]
JA Clinical Reports, 2021 Shunsuke Tachibana +2 more
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Clinical Pharmacokinetics and Pharmacodynamics of Remimazolam
Clinical PharmacokineticsRemimazolam is a benzodiazepine with a high affinity for the γ-aminobutyric acid type A-receptor thereby inducing sedation and amnesia. It is a short-acting drug, has a fast onset, short duration of action, and a predictable recovery profile. Remimazolam is metabolized mainly into CNS7054.
Bas T. de Jong +3 more
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Comparison of bispectral index and patient state index as measures of sedation depth during surgeries using remimazolam tosilate [PDF]
, 2023 Tang‐yuan‐meng Zhao +4 more
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Scientific ReportsRemimazolam, a novel intravenous anesthetic, has been proven to be safe and efficacious in the gastroscopy setting among the elderly. However, reports comparing the effectiveness and safety of using equivalent doses of remimazolam with propofol have not ...
Di Chen +4 more
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Anesthetic management with remimazolam for a patient with hereditary angioedema : a case report [PDF]
Background : Hereditary angioedema (HAE), a genetic disorder caused by C1-inhibitor deficiency or dysfunction, may cause mucosal edema in the upper airway during tracheal intubation and extubation.
343 +24 more
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PLOS OneObjective The optimal sedation strategy for gastrointestinal endoscopy remains debated. This study compared the efficacy and safety of remimazolam combined with etomidate versus propofol for procedural sedation during gastrointestinal endoscopy. Methods This single-center, randomized controlled clinical trial was performed from March 2024 to April ...
Baoyu Ma +3 more
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Long-term sedation with remimazolam besylate versus propofol in critically ill patients during invasive mechanical ventilation: a study protocol for a multicenter randomized non-inferior trial [PDF]
, 2023 Xiaobo Yang +10 more
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