Results 1 to 10 of about 166,471 (381)

Probiotics for induction of remission in Crohn's disease [PDF]

Cochrane Database of Systematic Reviews, 2008
Crohn's disease has a high morbidity and there is no known cure. Current treatments have multiple side effects and an effective treatment with minimal side effects is desired. Probiotics have been proposed as such a treatment but their efficacy is undetermined.
Andrew D, Butterworth, Adrian G, Thomas, Anthony Kwaku, Akobeng   +2 more
openaire   +3 more sources

Traditional corticosteroids for induction of remission in Crohn's disease [PDF]

Cochrane Database of Systematic Reviews, 2007
Historically, corticosteroids have been the most commonly used class of medication for induction of remission in Crohn's disease (CD). Corticosteroids down regulate production of inflammatory cytokines and interfere with NF-kappaB production, thereby blunting inflammatory response.The primary objective was to systematically review the efficacy and ...
Cynthia H. Seow, Eric I Benchimol, Anne M. Griffiths, A. Hillary Steinhart   +3 more
openaire   +4 more sources

Lupus nephritis management guidelines compared [PDF]

, 2015
In the past years, many (randomized) trials have been performed comparing the treatment strategies for lupus nephritis. In 2012, these data were incorporated in six different guidelines for treating lupus nephritis.
Bajema, IM, Bertsias, GK, Boumpas, DT, Gordon, C, Jayne, DR, Lightstone, L, Tesar, V, Wilhelmus, S   +7 more
core   +1 more source

Adalimumab for induction of remission in Crohn's disease

Cochrane Database of Systematic Reviews, 2017
Adalimumab is an IgG1 monoclonal antibody that targets and blocks tumor necrosis factor-alpha, a pro-inflammatory cytokine involved in the pathogenesis of Crohn's disease (CD). A significant proportion of people with CD fail conventional therapy or therapy with biologics or develop significant adverse events.
Brian G. Feagan, Vipul Jairath, Mohamad Abbass, Claire E Parker, Tran M Nguyen, Jeremy Cepek, Reena Khanna, John K MacDonald   +7 more
openaire   +4 more sources

"Society of Hematologic Oncology (SOHO) State of the Art Updates and Next Questions"-Treatment of ALL. [PDF]

, 2018
The outcome of adult acute lymphoblastic leukemia (ALL) has substantially improved by adopting pediatric-inspired regimens, and approximately half of the patients are nowadays cured.
Chiaretti, S, Hoelzer, D, Jabbour, E
core   +1 more source

Etrolizumab for induction of remission in ulcerative colitis

Cochrane Database of Systematic Reviews, 2015
Etrolizumab (rhuMAb beta7) is an anti-integrin that selectively targets the β7 subunits of the α4β7 and αEβ7 integrins, which are involved in the pathogenesis of ulcerative colitis.The objectives of this review were to assess the efficacy and safety of etrolizumab for induction of remission in ulcerative colitis.We searched PubMed, MEDLINE, EMBASE, and
Brian Bressler, Greg Rosenfeld, John K MacDonald, Claire E Parker   +3 more
openaire   +4 more sources

Detection of monosomy 7 in interphase cells of patients with myeloid disorders [PDF]

, 1990
Six patients, five with acute myeloid leukemia (AML) and one with a myelodysplastic syndrome (MDS), were found to have monosomy 7 by conventional cytogenetics at diagnosis.
Cremer, Thomas, Gezer, Sefer, Kolluri, Rukmini V., Manuelidis, L., Raza, Azra, Sait, Sheila   +5 more
core   +1 more source

Induction of remission in diabetes by lowering blood glucose

Frontiers in Endocrinology, 2023
As diabetes continues to grow as major health problem, there has been great progress in understanding the important role of pancreatic beta-cells in its pathogenesis. Diabetes develops when the normal interplay between insulin secretion and the insulin sensitivity of target tissues is disrupted.
Gordon C. Weir, Susan Bonner-Weir
openaire   +3 more sources

Biotin Supplementation Ameliorates Murine Colitis by Preventing NF-κB Activation. [PDF]

, 2020
Background & aimsBiotin is a water-soluble vitamin that is indispensable for human health. Biotin deficiency can cause failure-to-thrive, immunodeficiency, alopecia, dermatitis, and conjunctivitis.
Cahalan, Michael D, Hwang, Michael, Nakasaki, Manando, Sabui, Subrata, Said, Hamid M, Skupsky, Jonathan   +5 more
core  

Feasibility of azacitidine added to standard chemotherapy in older patients with acute myeloid leukemia - a randomised SAL pilot study [PDF]

, 2012
INTRODUCTION: Older patients with acute myeloid leukemia (AML) experience short survival despite intensive chemotherapy. Azacitidine has promising activity in patients with low proliferating AML.
Berdel, Wolfgang E., Brandts, Christian Hubertus, Bug, Gesine, Büchner, Thomas, Dührsen, Ulrich, Ehninger, Gerhard, Gerss, Joachim, Koschmieder, Anja, Koschmieder, Steffen, Krug, Utz, Müller-Tidow, Carsten, Noppeney, Richard, Röllig, Christoph, Schaich, Markus, Schwammbach, Daniela, Serve, Hubert, Steffen, Björn, Stelljes, Matthias, Thiede, Christian, Tidow, Nicola   +19 more
core   +7 more sources