Results 11 to 20 of about 158,388 (335)
Remission induction in acute myeloid leukemia [PDF]
Inducing a complete remission (CR) in patients with acute myeloid leukemia is a prerequisite to long-term disease control with subsequent post-remission consolidation chemotherapy or allogeneic hematopoietic stem cell transplantation. The use of 7 days of infusional cytarabine and 3 days of daunorubicin or idarubicin (7 + 3) has become the standard of ...
Eytan M. Stein, Martin S. Tallman
openalex +5 more sources
Probiotics for induction of remission in Crohn's disease [PDF]
Crohn's disease has a high morbidity and there is no known cure. Current treatments have multiple side effects and an effective treatment with minimal side effects is desired. Probiotics have been proposed as such a treatment but their efficacy is undetermined.
Andrew D Butterworth+2 more
openalex +3 more sources
Traditional corticosteroids for induction of remission in Crohn's disease [PDF]
Historically, corticosteroids have been the most commonly used class of medication for induction of remission in Crohn's disease (CD). Corticosteroids down regulate production of inflammatory cytokines and interfere with NF-kappaB production, thereby blunting inflammatory response.The primary objective was to systematically review the efficacy and ...
Eric I. Benchimol+3 more
openalex +4 more sources
VAD chemotherapy as remission induction for multiple myeloma [PDF]
A total of 142 patients with multiple myeloma received VAD as remission induction therapy. Seventy-five were previously untreated and 67 had relapsed (31) or refractory disease (36). Vincristine (total dose 1.6 mg) was infused with doxorubicin 36 mg m-2 by continuous ambulatory pump over 4 days. In addition, oral dexamethasone 40 mg day-1 was given for
Heather Anderson+7 more
openalex +3 more sources
Probiotics for induction of remission in Crohn's disease
Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract, in which the pathogenesis is believed to be partly influenced by the gut microbiome. Probiotics can be used to manipulate the microbiome and have therefore been considered as a potential therapy for CD.
Limketkai, Berkeley N+3 more
openaire +4 more sources
Glutamine for induction of remission in Crohn's disease [PDF]
Crohn's disease is a chronic relapsing condition of the alimentary tract with a high morbidity secondary to bowel inflammation. Glutamine plays a key role in maintaining the integrity of the intestinal mucosa and has been shown to reduce inflammation and disease activity in experimental models of Crohn's disease.To evaluate the efficacy and safety of ...
Akobeng, Anthony+2 more
openaire +3 more sources
Methotrexate for induction of remission in ulcerative colitis [PDF]
Ulcerative colitis (UC) is a chronic inflammatory bowel disease. Corticosteroids and 5-aminosalicylates are the most commonly used therapies. However, many patients require immunosuppressive therapy for steroid-refractory and steroid-dependent disease.
John K MacDonald+3 more
openaire +3 more sources
Probiotics for induction of remission in ulcerative colitis
Ulcerative colitis is an inflammatory condition affecting the colon, with an annual incidence of approximately 10 to 20 per 100,000 people. The majority of people with ulcerative colitis can be put into remission, leaving a group who do not respond to first- or second-line therapies.
Kaur, Lakhbir+5 more
openaire +3 more sources
Antibiotics for the induction and maintenance of remission in ulcerative colitis [PDF]
Antibiotics have been considered to treat ulcerative colitis (UC) due to their antimicrobial properties against intestinal bacteria linked to inflammation. However, there are concerns about their efficacy and safety.To determine whether antibiotic therapy is safe and effective for the induction and maintenance of remission in people with UC.We searched
Gordon, Morris+3 more
openaire +3 more sources
Detection of monosomy 7 in interphase cells of patients with myeloid disorders [PDF]
Six patients, five with acute myeloid leukemia (AML) and one with a myelodysplastic syndrome (MDS), were found to have monosomy 7 by conventional cytogenetics at diagnosis.
Cremer, Thomas+5 more
core +1 more source