The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors. Pathogenic mutations in UBE3B result in neurodevelopmental disease, including intellectual disability, lack of speech, and ASD.
Shayal Vashisth +7 more
wiley +1 more source
The evidence base for ranger patrol effectiveness in conservation and how to improve it
ABSTRACT Ranger patrols are a cornerstone of wildlife protection efforts around the world and occur across all ecological governance systems. Evidence that patrols reduce threats to wildlife and enable their recovery has not been systematically examined previously.
Trina Rytwinski +19 more
wiley +1 more source
REML estimation: asymptotic behavior and related topics
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Selection of sugarcane families and parents by Reml/Blup
Were evaluated 113 full-sib families obtained by unbalanced diallel matings in three experiments in an augmented block design (ABD) planted side by side in the same area. The individual and joint analyses of the experiments were performed by the Reml/Blup method.
M.H.P. Barbosa +4 more
openaire +1 more source
Predicting cervical cancer DNA methylation from genetic data using multivariate CMMP
Abstract Epigenetic modifications link the environment to gene expression and play a crucial role in tumour development. DNA methylation, in particular, is gaining attention in cancer research, including cervical cancer, the focus of this study.
Hang Zhang +5 more
wiley +1 more source
Software Selegen-REML/BLUP: a useful tool for plant breeding
The software Selegen-REML/BLUP uses mixed models, and was developed to optimize the routine of plant breeding programs. It addresses the following plants categories: allogamous, automagous, of mixed mating system, and of clonal propagation.
Marcos Deon Vilela de Resende
doaj
A genome-wide association study demonstrates significant genetic variation for fracture risk in Thoroughbred racehorses [PDF]
Background: Thoroughbred racehorses are subject to non-traumatic distal limb bone fractures that occur during racing and exercise. Susceptibility to fracture may be due to underlying disturbances in bone metabolism which have a genetic cause.
Blott, Sarah C. +8 more
core +4 more sources
Non‐negative Gaussian estimation of variance components in random effects models
Abstract When used to estimate variance components (VCs), confidence intervals (CIs) can be truncated at zero, have a point estimate not in the quoted CI, be empty with positive probability, or be all‐inclusive. This is because they have conflicting dual roles, since they are considered to cover the parameter with a specified probability while also ...
André Plante, Michael Plante
wiley +1 more source
Wald consistency and the method of sieves in REML estimation [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Cultural Pathways to Sustainability: How Organizational Cultures Shape Firms' ESG Performance
ABSTRACT Understanding how organizational culture shapes firms' environmental, social, and governance (ESG) performance is essential for advancing effective sustainability management. Culture reflects shared values and norms that shape how firms enact ESG principles.
Marianna Delegach +2 more
wiley +1 more source

