Results 31 to 40 of about 855,004 (311)
Frontiers in Pharmacology, 2021 Aims: The acetylcholine-activated inward rectifier potassium current (IKACh) has been proposed as an atrial-selective target for the treatment of atrial fibrillation (AF).
Vladimír Sobota +8 more
doaj +1 more source
NoRC, a novel chromatin remodeling complex involved in ribosomal RNA gene silencing [PDF]
, 2004 Regulation of gene expression takes place in the nucleus in a highly structured and condensed nucleoprotein environment, called chromatin (Felsenfeld and Groudine, 2003; Khorasanizadeh, 2004; Vaquero et al., 2003).
Strohner, Ralf
core +1 more source
SHH Signaling Pathway Drives Pediatric Bone Sarcoma Progression
Cells, 2020 Primary bone tumors can be divided into two classes, benign and malignant. Among the latter group, osteosarcoma and Ewing sarcoma are the most prevalent malignant primary bone tumors in children and adolescents.
Frédéric Lézot +4 more
doaj +1 more source
The Journal of Reproduction and Development, 2022 It is now approximately 25 years since the sheep Dolly, the first cloned mammal where the somatic cell nucleus from an adult donor was used for transfer, was born.
Helena FULKA +4 more
doaj +1 more source
The Journal of Thoracic and Cardiovascular Surgery, 2015 Root remodeling was proposed as valve-preserving root replacement to treat patients with aortic regurgitation and root aneurysm. The objective of this retrospective study was to review 18 years of experience with root remodeling and to identify predictors of valve durability.Between October 1995 and December 2013, root remodeling was performed in 747 ...
Schäfers, Hans-Joachim +6 more
openaire +2 more sources
Ribosomopathies: New Therapeutic Perspectives
Cells, 2020 Ribosomopathies are a group of rare diseases in which genetic mutations cause defects in either ribosome biogenesis or function, given specific phenotypes.
Emilien Orgebin +6 more
doaj +1 more source
eLife, 2013 Biochemical assays reveal that nucleosome maturation and chromatin remodelling by the motor protein Chd1 are distinct, separable enzymatic activities.
Bouazoune, Karim, Kingston, Robert
openaire +5 more sources
Nature Communications, 2018 Cardiac progenitor cells (CPCs) form cardiomyocytes, pericytes, smooth muscle and endothelial cells during embryonic development. Here, the authors characterize mouse CPCs marked by Nkx2.5 and Isl1 from E7.5 to E9.5 by single cell RNA-seq and ATAC-seq ...
Guangshuai Jia +10 more
doaj +1 more source
Кардиоваскулярная терапия и профилактика, 2021 Aim. To study the relationship between plasma aldosterone level and left ventricular (LV) structure and function in heart failure with preserved ejection fraction (HFpEF).Material and methods.
A. N. Shevelok
doaj +1 more source
Nature Reviews Neuroscience, 2020 In the hippocampus of adult mice, neuronally expressed interleukin-33 acts as a signal for microglial cell-mediated extracellular matrix remodelling, regulating synaptic plasticity and promoting memory consolidation.
openaire +2 more sources