Results 141 to 150 of about 2,124,411 (292)

Is Implant Removal After Thoracolumbar Fracture Fixation Truly Necessary? A Systematic Review and Meta-Analysis of Radiological, Functional and Safety Outcomes. [PDF]

Global Spine J
Viswanathan VK, Muthu S, Kolarpatti Ponnusamy DV, Hiatt L, Rajappan Chandra SK, Sharun K, Theiss S.   +6 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Time Required to Retreat Carrier-Based Obturation: Comparison Between Two Techniques at Two Levels of Experience. [PDF]

Dent J (Basel)
Salvadori M, Audino E, Facchinetti M, Kumar V, Alovisi M, Visconti L, Salgarello S.   +6 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Removal of Bisphenol A, Bisphenol S, and Estrogenic Activity from Real Wastewater Using a Multi-stage IFAS System. [PDF]

Bull Environ Contam Toxicol
do Amaral AF, da Silva ASA, Cunha DL, de O M Cunha PM, Coutinho R, Marques M.   +5 more
europepmc   +1 more source

Removed

, 2017
REMOVED
openaire   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Enhanced stability and reusability of metagenomic laccase via immobilization on functionalized mesoporous silica for antibiotic contaminant removal. [PDF]

Sci Rep
Ariaeenejad S, Abedanzadeh S.
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Polymorph II Cellulose Nanocrystals Derived from Oil Palm Empty Fruit Bunches for High-Efficiency COD Removal in Industrial Wastewater. [PDF]

Nanomaterials (Basel)
Pomalaya-Velasco J, Bendezú-Roca Y, Canchanya-Huaman Y, Ramos-Guivar JA.   +3 more
europepmc   +1 more source