Results 11 to 20 of about 4,080,709 (367)

Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure

New England Journal of Medicine, 2020
Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure in patients regardless of the presence or absence of diabetes.
M. Packer, S. Anker, J. Butler, G. Filippatos, S. Pocock, P. Carson, J. Januzzi, S. Verma, H. Tsutsui, M. Brueckmann, W. Jamal, K. Kimura, J. Schnee, C. Zeller, D. Cotton, E. Bocchi, M. Böhm, D. Choi, V. Chopra, E. Chuquiure, N. Giannetti, S. Janssens, Jian Zhang, J. G. González Juanatey, S. Kaul, H. Brunner-la Rocca, B. Merkely, S. Nicholls, S. Perrone, I. Piña, P. Ponikowski, N. Sattar, M. Senni, M. Séronde, J. Špinar, I. Squire, S. Taddei, C. Wanner, F. Zannad   +38 more
semanticscholar   +1 more source

Mathematical Model of Volume Kinetics and Renal Function after Burn Injury and Resuscitation [PDF]

Burns, 47(2), pp.371-386 (2021), 2021
This paper presents a mathematical model of blood volume kinetics and renal function in response to burn injury and resuscitation, which is applicable to the development and non-clinical testing of burn resuscitation protocols and algorithms. Prior mathematical models of burn injury and resuscitation are not ideally suited to such applications due to ...
arxiv   +1 more source

A Hybrid Approach to Full-Scale Reconstruction of Renal Arterial Network [PDF]

Sci Rep 13, 7569 (2023), 2023
The renal vasculature, acting as a resource distribution network, plays an important role in both the physiology and pathophysiology of the kidney. However, no imaging techniques allow an assessment of the structure and function of the renal vasculature due to limited spatial and temporal resolution.
arxiv   +1 more source

Multiorgan and Renal Tropism of SARS-CoV-2

New England Journal of Medicine, 2020
Multiorgan and Renal Tropism of SARS-CoV-2 In this autopsy series, the authors found that SARS-CoV-2 has an organotropism beyond the respiratory tract, including the kidneys, heart, liver, and brai...
Victor G. Puelles, M. Lütgehetmann, M. Lindenmeyer, J. Sperhake, M. N. Wong, L. Allweiss, S. Chilla, A. Heinemann, Nicola Wanner, Shuya Liu, Fabian Braun, Shun Lu, S. Pfefferle, A. Schröder, C. Edler, O. Gross, M. Glatzel, D. Wichmann, T. Wiech, S. Kluge, K. Pueschel, M. Aepfelbacher, T. Huber   +22 more
semanticscholar   +1 more source

Publisher Correction to: Renal Replacement Therapy, volume 5

Renal Replacement Therapy, 2019
An error occurred during the publication of a number of articles in Renal Replacement Therapy. Several articles were published in volume 5 with a duplicate citation number.
Renal Replacement Therapy
doaj   +1 more source

Renal impairment in a rural African antiretroviral programme [PDF]

, 2009
Background: There is little knowledge regarding the prevalence and nature of renal impairment in African populations initiating antiretroviral treatment, nor evidence to inform the most cost effective methods of screening for renal impairment.
A Mocroft, A Reid, Ahmed Adam, Cara Franey, Deborah Knott, FA Post, Graham S Cooke, HE van Deventer, J Roe, JJ Bourgoignie, K Wools-Kaloustian, Marie-Louise Newell, Martin Dedicoat, MJ Siedner, MR Nelson, Richard J Lessells, SD Cohen, SK Gupta, T Barnighausen, TE Gerntholtz, Till Barnighausen, TK Rao, TM Han, WHO   +23 more
core   +3 more sources

Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy.

New England Journal of Medicine, 2019
BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium-glucose cotransporter 2 (SGLT2), exploratory results have ...
V. Perkovic, M. Jardine, B. Neal, Severine Bompoint, H. Heerspink, D. Charytan, Robert Edwards, R. Agarwal, G. Bakris, S. Bull, C. Cannon, G. Capuano, P. Chu, D. de Zeeuw, T. Greene, A. Levin, C. Pollock, D. Wheeler, Yshai Yavin, Hong Zhang, B. Zinman, G. Meininger, B. Brenner, K. Mahaffey   +23 more
semanticscholar   +1 more source

Ornipressin in the treatment of functional renal failure in decompensated liver cirrhosis [PDF]

, 1991
In 11 patients with decompensated cirrhosis and deteriorating renal function, the effect of the vasoconstrictor substance 8-ornithin vasopressin (ornipressin; POR 8; Sandoz, Basel, Switzerland) on renal function, hemodynamic parameters, and humoral ...
Alexander L. Gerbes, Anton Laggner, Arendt, Barratt-Boyes, Barry, Bauch, Brenner, Bruno Schneeweiss, Burnett, Cohn, Davies, Epstein, Epstein, Epstein, Fernandez-Seara, Fischer, Fried, Fyrquist, Ganger, Ganong, Georg Grimm, Gerbes, Gerbes, Gerbes, Gerbes, Gornel, Granger, Haber, Harald Reither, Heide Hörtnagl, Heinrich, Heyndrickx, Hintze, Holtz, Hörtnagl, Katsube, Kew, Klepetko, Koepke, Kontos, Kotelanski, Kurt Lenz, Lancestremere, Lenz, Lenz, Lenz, López, Manning, Marin-Grez, Murray, Needleman, Nicholls, Oshima, Panos, Petrillo, Rainer Schmid, Richards, Salerno, Salerno, Schenker, Schmid, Schrier, Shapiro, Siegel, Solis-Herruzo, Wernze, Wilfred Druml   +66 more
core   +1 more source

Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma.

New England Journal of Medicine, 2015
BACKGROUND Nivolumab, a programmed death 1 (PD-1) checkpoint inhibitor, was associated with encouraging overall survival in uncontrolled studies involving previously treated patients with advanced renal-cell carcinoma.
R. Motzer, B. Escudier, D. McDermott, S. George, H. Hammers, S. Srinivas, S. Tykodi, J. Sosman, G. Procopio, E. Plimack, D. Castellano, T. Choueiri, H. Gurney, F. Donskov, P. Bono, J. Wagstaff, T. Gauler, Takeshi Ueda, Y. Tomita, F. Schutz, C. Kollmannsberger, J. Larkin, A. Ravaud, J. Simon, Li-an Xu, I. Waxman, Padmanee Sharma   +26 more
semanticscholar   +1 more source

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim, Schlöndorff, Detlef   +1 more
core   +1 more source