Results 191 to 200 of about 591,781 (298)

Nutrient intake and renal cancer: molecular pathways and mechanistic insights into the protective role of dietary components. [PDF]

Front Nutr
Chen P, Bi X, Tian R, Zhang Q.
europepmc   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

Biomaterial-Driven Integrated Therapy for Renal Cell Carcinoma: Renal Cancer Control and Kidney Injury Repair. [PDF]

Research (Wash D C)
Song J, Zhang T, Li M, Liu W, Chen T, Qiang H, Wang L, Wu Z, Gao J.   +8 more
europepmc   +1 more source

Macrophage‐to‐Myofibroblast Transdifferentiation Contributes to Pulmonary Fibrosis via the MERTK‐SPP1‐SRC‐TKS5 Signaling Axis

Advanced Science, EarlyView.
MERTK is upregulated in fibrotic macrophages and regulates the expression and activity of SRC and TKS5 through SPP1, mediating transdifferentiation of macrophages‐to‐myofibroblasts (MMT) and promoting pulmonary fibrosis. The figure was created with BioRender.com.
Yungeng Wei, Hua Guo, Xiangsheng Yang, Xiao Xiao Tang   +3 more
wiley   +1 more source

Metachronous bilateral renal cancer with immune checkpoint blockade-mediated eradication of bone metastasis: case report. [PDF]

Front Oncol
Metodiev D, Borisov T, Da Costa PA, Redissi A, Cremer I, Petrova M, Vano YA, Roumenina LT, Ferdinandov D.   +8 more
europepmc   +1 more source

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

Advanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander, Maria del Pilar Palacios Cisneros, Clara Certa, Megan Stierli, Katharina Beck, Nicolas Färber, Lisa Blank, Fiona Tanner, Eric Mühlberg, Sabrina Wohlfart, Christian Kleist, Jörg Huwyler, Gert Fricker, Walter Mier, Philipp Uhl   +14 more
wiley   +1 more source

Connective tissue growth factor contributes to resistance to anti-angiogenic therapies in renal cancer. [PDF]

Theranostics
Teisseire M, Karaulic A, Parola J, Totobesola M, Borchiellini D, Pace-Loscos T, Schiappa R, Chamorey E, Durivault J, Dufies M, Ambrosetti D, Luciano F, Gao J, Cao Y, Pagès G, Giuliano S.   +15 more
europepmc   +1 more source

Triple‐Negative Breast Cancer Cells Utilize IL8 and CXCL1 to Suppress NK Cells’ Function and Facilitate Cancer Metastasis

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) cells evade natural killer (NK) cell immunity by secreting IL8 and CXCL1. These chemokines suppress NK cells’ function via CXCR1/2 and enhance cancer cells’ survival through PD‐L1 upregulation and BCL‐2 anti‐apoptotic signaling.
Mingheng Yuan, Hongmei Yang, Renfei Wu, Meng Hao, Xiangpeng Chu, Chuxia Deng, Kathy Qian Luo   +6 more
wiley   +1 more source

Renal cancer survival in clear cell renal cancer compared to other types of tumor histology: A population-based cohort study. [PDF]

PLoS One
Sepp T, Poyhonen A, Uusküla A, Kotsar A, Veitonmäki T, Tammela TLJ, Baburin A, Murtola TJ.   +7 more
europepmc   +1 more source

In vitro sensitivity testing of human renal cell carcinoma with cytostatic agents and interferon alpha-2a [PDF]

, 1991
R. Schlick, Jonas, Udo, Allhoff, E. P., G. Lenis, S. Liedke, Liedke, S. G., U. Jonas, E. Allhoff, Stief, Christian Georg, C. G. Stief, Anton, P., Riese, W. de, W. de Riese, P. Anton, Schlick, R. W.   +14 more
core   +1 more source