Results 71 to 80 of about 6,382,401 (301)

Gallbladder Metastasis from Renal Cell Carcinoma

Case Reports in Oncology, 2010
A 73-year-old female was operated with radical nephrectomy and cholecystectomy for renal cell carcinoma and suspected gallstones after 9 courses of sunitinib treatment.
Takashi Kawahara, Hisashi Ohshiro, Zenkichi Sekiguchi, Mitsuko Furuya, Kazuhiro Namura, Hiroki Itoh, Futoshi Sano, Kaoru Kawaji, Narihiko Hayashi, Kazuhide Makiyama, Noboru Nakaigawa, Takehiko Ogawa, Hiroji Uemura, Masahiro Yao, Yoshinobu Kubota   +14 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

The expression of RNA-binding protein RBM38 decreased in renal cell carcinoma and represses renal cancer cell proliferation, migration, and invasion

Tumor Biology, 2017
RBM38, a member of RNA recognition motif family of RNA-binding proteins, can regulate the expression of diverse targets by influencing their messenger RNA stability and play a vital role in cancer development.
Wen Huang, Xiao-Long Wei, WeiWei Ni, Mengda Cao, Ling Meng, Haiwei Yang   +5 more
doaj   +1 more source

Double renal cell carcinoma with histological type of clear cell carcinoma and papillary carcinoma in the same kidney concurrently treated with robot‐assisted partial nephrectomy

IJU Case Reports, 2022
Introduction The presence of two different histologic types of renal cell carcinoma in the same kidney is rare in clinical practice. This report describes a patient with ipsilateral renal cell carcinomas, consisting of a clear cell renal cell carcinoma ...
Teruki Shimizu, Fumiya Hongo, Hikaru Takahashi, Atsuko Fujihara, Osamu Ukimura   +4 more
doaj   +1 more source

Clear cell renal cell carcinoma and papillary renal cell carcinoma: differentiation of distinct histological types with multiphase CT [PDF]

, 2013
PURPOSEConventional clear cell renal cell carcinoma (ccRCC) and papillary renal cell carcinoma (pRCC) have different behavioral characteristics and clinical management strategies (nephrectomy vs. nephron-sparing surgery).
David Laszlo Tarnoki, Peter Nyirady, Bence Fejer, Attila Szendroi, A. Marcell Szasz, Dora Kekesi, Viktor Berczi, Pal Bata, Janos Gyebnar, Adam Domonkos Tarnoki, Kinga Karlinger   +10 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Survival Outcomes in Older Adults With Axial Spondyloarthritis and Concomitant Cancer

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to determine survival outcomes in older adults with axial spondyloarthritis (axSpA) and concomitant cancer. Methods We conducted a population‐based study using Medicare claims data linked to Surveillance, Epidemiology, and End Results data to determine overall survival (OS) and cancer‐specific survival (CSS) in
Savannah Bowman, Mei Li, Xiudong Lei, Hui Zhao, Juan I. Ruiz, Sharon H. Giordano, Alexis R. Ogdie, Maria E. Suarez‐Almazor   +7 more
wiley   +1 more source

MiR-122 promotes renal cancer cell proliferation by targeting Sprouty2

Tumor Biology, 2017
MicroRNAs are short non-coding RNAs, which have been implicated in several biological processes. Aberrant expression of the microRNA miR-122 has frequently been reported in malignant cancers.
Zijie Wang, Chao Qin, Jing Zhang, Zhijian Han, Jun Tao, Qiang Cao, Wanli Zhou, Zhen Xu, Chunchun Zhao, Ruoyun Tan, Min Gu   +10 more
doaj   +1 more source

Intravascular large B‐cell lymphoma in renal cell carcinoma incidentally detected by robot‐assisted partial nephrectomy

IJU Case Reports, 2022
Introduction Intravascular large B‐cell lymphoma is a rare and aggressive type of extranodal large B‐cell lymphoma. Although intravascular large B‐cell lymphoma can invade various organs, renal involvement has been rarely reported. Synchronous occurrence
Michio Noda, Yutaka Enomoto, Yukari Shirasugi, Sumiyo Ando, Yukimasa Matsuzawa, Haruki Kume   +5 more
doaj   +1 more source