Results 81 to 90 of about 577,818 (354)

Intradural spinal metastasis of renal cell cancer. Report of a case and review of 26 published cases [PDF]

, 2018
Metastatic disease in the intradural compartment of the spine is a rare manifestation of cancer. We report the case of an 82-year-old patient with an intradural, extramedullary metastasis of renal cell carcinoma in the cervical spine. A literature search
Cordier, Dominik, Frank, Stephan, Jost, Gregory, Merlo, Adrian, Zimmerer, Stephan   +4 more
core  

Gene amplification and overexpression of HER2 in renal cell carcinoma [PDF]

, 2002
Objective To determine the frequency of HER2 genetic abnormalities in renal cell carcinoma (RCC) and hence assess the potential suitability of Herceptin(TM) immunotherapy.
Aitchison, M., Bartlett, J.M.S., Latif, Z., Underwood, M.A., Watters, A.D.   +4 more
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

MiR-122 promotes renal cancer cell proliferation by targeting Sprouty2

Tumor Biology, 2017
MicroRNAs are short non-coding RNAs, which have been implicated in several biological processes. Aberrant expression of the microRNA miR-122 has frequently been reported in malignant cancers.
Zijie Wang, Chao Qin, Jing Zhang, Zhijian Han, Jun Tao, Qiang Cao, Wanli Zhou, Zhen Xu, Chunchun Zhao, Ruoyun Tan, Min Gu   +10 more
doaj   +1 more source

Complexity of the genomic landscape of renal cell carcinoma: Implications for targeted therapy and precision immuno-oncology [PDF]

, 2017
The topic of tumoral heterogeneity at the genetic level has become relevant in various solid origin tumors, particularly in an age of targeted treatment.
Cheng, Liang, Sanfrancesco, Joseph M.
core   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Ovarian metastases from renal cell carcinoma: A report of two cases

Fujita Medical Journal
Renal cell carcinoma is a malignant tumor that is prone to distant metastasis, primarily developing in the lungs, bones, lymph nodes, liver, and brain.
Junichi Takagi, Ryoko Ichikawa, Kyohei Takada, Akiko Ohwaki, Mayuko Ito, Yutaka Torii, Hiroyuki Nomura, Haruki Nishizawa   +7 more
doaj   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Thyroid-like Follicular Renal Cell Carcinoma: An Emerging Entity

Archives of Medicine and Health Sciences
Thyroid-like follicular renal cell carcinoma is an extremely rare tumor. The tumors show a striking resemblance to well-differentiated thyroid follicular neoplasm but can be differentiated on immunohistochemistry due to lack of thyroglobulin and thyroid ...
Sarita Asotra, Himani Thakur, Kailash Chander Barwal   +2 more
doaj   +1 more source

DAB2IP Plays Important Clinical Significance and Correlates With Immune Infiltration in Renal Cell Carcinoma

Technology in Cancer Research & Treatment, 2020
Background: Disabled homolog 2-interacting protein is a new member of the Ras GTPase superfamily involved in the regulation of cell proliferation, apoptosis, and metastasis.
Haoyuan Cao MM, Jiandong Zhang MD, Wei Wang MD   +2 more
doaj   +1 more source