Toxins, 2019 Gut microbiota-dependent Trimethylamine-N-oxide (TMAO) has been reported to be strongly linked to renal function and to increased cardiovascular events in the general population and in Chronic Kidney Disease (CKD) patients.
Caroline C. Pelletier +9 more
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Noninvasive Real-Time Characterization of Renal Clearance Kinetics in Diabetic Mice after Receiving Danshensu Treatment [PDF]
, 2018 Danshensu (DSS) is an active ingredient extracted from the root of the Danshen that could ameliorate oxidative stress via upregulation of heme oxygenase- (HO-) 1.
Gao, L +11 more
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Allium sativum aqueous extract prevents potassium dichromate-induced nephrotoxicity and lipid oxidation in rats [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2014 Context: The potassium dichromate (K2Cr2O7) induces nephrotoxicity by oxidative stress mechanisms. Aims: To study the potential protection of an aqueous extract of Allium sativum against the K2Cr2O7-induced nephrotoxicity and lipid oxidation in rats ...
Sergio L. Becerra-Torres +3 more
doaj
Ultrasmall BiOI Quantum Dots with Efficient Renal Clearance for Enhanced Radiotherapy of Cancer
Advanced Science, 2020 Emerging strategies involving nanomaterials with high‐atomic‐number elements have been widely developed for radiotherapy in recent years. However, the concern regarding their potential toxicity caused by long‐term body retention still limits their ...
Xin Wang +6 more
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Incubation Time Influences Organic Anion Transporter 1 Kinetics and Renal Clearance Predictions
Journal of Xenobiotics, 2023 Accurate predictions of drug uptake transporter involvement in renal excretion of xenobiotics require determination of in vitro transport kinetic parameters under initial-rate conditions. The purpose of the present study was to determine how changing the
Aaron O. Buaben, Ryan M. Pelis
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Bioengineering & Translational Medicine, 2020 Chronic kidney disease (CKD) affects 15% of the US adult population. However, most clinically available drugs for CKD show low bioavailability to the kidneys and non‐specific uptake by other organs which results in adverse side effects. Hence, a targeted,
Yi Huang +3 more
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Rapid Tumor Targeting of Renal-Clearable ZW800-1 Conjugate for Efficient Photothermal Cancer Therapy
Biomedicines, 2021 The combination of near-infrared (NIR) fluorophores and photothermal therapy (PTT) provides a new opportunity for safe and effective cancer treatment. However, the precise molecular design of functional NIR fluorophores with desired properties, such as ...
Min Ho Park +4 more
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Renal Clearance on Upper Urinary Tract Disturbances [PDF]
, 1959 72 patieuts with upper urinary tract disturbances were examined by renal clearance, water test and PSP test. The relationship between these three kinds or renal funetion test was observed by the calculation of correlation coefficient. 1.
Keiko Hayakawa, Hayakawa, Keiko
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A Hybrid Jigsaw Approach to Teaching Renal Clearance Concepts [PDF]
, 2009 To evaluate the effectiveness of using a jigsaw cooperative learning approach to teach basic concepts of renal clearance to pharmacy ...
Pollack, Gary M., Persky, Adam M.
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Creatinine Trends and Patterns in Neonates Undergoing Whole Body Hypothermia: A Systematic Review
Children, 2021 Many neonates undergoing whole body hypothermia (WBH) following moderate to severe perinatal asphyxia may also suffer from renal impairment. While recent data suggest WBH-related reno-protection, differences in serum creatinine (Scr) patterns to ...
Noor Borloo +4 more
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