Results 51 to 60 of about 10,774 (174)

Severe Immune‐Related Neurological Adverse Events Associated With Immune Checkpoint Inhibitor Treatment: A Retrospective Single‐Center Study

European Journal of Neurology, Volume 33, Issue 6, June 2026.
In a cohort of 2043 patients treated with immune checkpoint inhibitors (ICI), severe neurological immune‐related adverse events (n‐irAEs) occurred in 0.5% of cases. These events predominantly involved the peripheral nervous system (PNS) and showed variable onset.
Anna Grisold, Angelika M. Starzer, Sara Silvaieh, Martin Krenn, Marie‐Bernadette Aretin, Manuela Schmidinger, Julia M. Ressler, Stephan Polterauer, Thomas Berger, Matthias Preusser, Anna S. Berghoff   +10 more
wiley   +1 more source

Deep Phenotyping of F64L Mutation in a Multicentric Cohort of Patisiran‐Treated Hereditary Transthyretin Amyloidosis Patients (Patisiranitaly)

European Journal of Neurology, Volume 33, Issue 6, June 2026.
ABSTRACT Background The F64L variant is among the most frequent TTR mutations in Italy, typically associated with a predominantly neurologic phenotype and limited cardiac involvement. Methods Data from 181 ATTRv patients in the multicenter Patisiranitaly database treated with Patisiran since 2020 were analyzed. Neurologic impairment scores, Norfolk QoL‐
Marco Ceccanti, Pietro Guaraldi, Angela Romano, Giovanni Antonini, Alessandro Barilaro, Chiara Briani, Marco Burattini, Micol Gianoli, Giulia Carlini, Vittoria Cianci, Marco Currò Dossi, Daniela Di Lisi, Antonio Di Muzio, Adele Ratti, Massimiliano Filosto, Sabrina Gasverde, Chiara Gemelli, Luca Gentile, Mariangela Goglia, Luca Leonardi, Simone Longhi, Antonio Lotti, Fiore Manganelli, Anna Mazzeo, Sofia Maria Augello, Giammarco Milella, Giuseppina Novo, Davide Pareyson, Silvia Fenu, Giovanni Palumbo, Cristina Petrelli, Loris Poli, Luca Guglielmo Pradotto, Massimo Russo, Alessandro Salvalaggio, Maria Ausilia Sciarrone, Luigi Sellitti, Matteo Tagliapietra, Stefano Tozza, Mariagiovanna Castiglia, Mara Turri, Lorenzo Verriello, Cristina Chimenti, Francesca Vitali, Filippo Brighina, Nicasio Rini, Maurizio Inghilleri, Roberto D'Angelo, Domenico Abelardo, Chiara Cambieri, Laura Libonati, Federica Moret, Marco Luigetti, Vincenzo Di Stefano   +53 more
wiley   +1 more source

Technical aspects of renal denervation in end-stage renal disease patients with challenging anatomy

Diagnostic and Interventional Radiology, 2014
We describe our preliminary experience with percutaneous renal denervation in end-stage renal disease patients with resistant hypertension and challenging anatomy, in terms of the feasibility, safety, and efficacy of this procedure.
Alessio Spinelli, Valerio Da Ros, Daniele Morosetti, Silvia D’Onofrio, Valentina Rovella, Nicola Di Daniele, Giovanni Simonetti   +6 more
doaj   +1 more source

Adverse Drug Reaction Study of Botulinum Toxin‐A in the Real World

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Despite the increasing use of botulinum toxin type A (BoNT‐A) in aesthetic and therapeutic applications, its real‐world adverse drug reaction (ADR) profile remains incompletely characterized. Current evidence relies largely on small‐scale clinical observations rather than large, systematic analyses.
Jiaxu Gu, Yue Sun, Kexin Chen, Jieyi Wang, Bingcheng Lu, Hongqiang Xie, Xiaoming Liu, Cong Huang, Xingling Jian, Bo Yu   +9 more
wiley   +1 more source

Renal Denervation

Journal of the American College of Cardiology
Arterial hypertension is a major risk factor for cardiovascular disease. Despite treatment recommendations, including lifestyle changes and use of combination drug treatment, a consistent fraction of hypertensive patients fails to achieve adequate blood pressure targets recommended by current guidelines.
Monica Tung, Taisei Kobayashi, Rajesh V. Swaminathan, Debbie L. Cohen, Dmitriy N. Feldman, Brian Fulton   +5 more
  +6 more sources

Phenol Neurolysis in Pain and Palliative Medicine

Pain Practice, Volume 26, Issue 5, June 2026.
ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Jeroen H. A. Creemers, Rachel J. H. Smits, Alopi M. Patel, Robert T. M. van Dongen, Cornelis K. Kramers, Jacqueline M. Bos, Selina E. I. van der Wal   +6 more
wiley   +1 more source

Adherence to Antihypertensive Medication in Treatment‐Resistant Hypertension Undergoing Renal Denervation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundAdherence to medication has been repeatedly proposed to represent a major cause of treatment‐resistant hypertension (TRH); however, treatment decisions such as treating TRH with renal denervation depend on accurate judgment of adherence.
Roland E. Schmieder, Christian Ott, Axel Schmid, Stefanie Friedrich, Iris Kistner, Tilmann Ditting, Roland Veelken, Michael Uder, Stefan W. Toennes   +8 more
doaj   +1 more source

Preferential renal tubular injury and increased renal sympathetic activity occur during the early stages of DOCA‐salt hypertension in male rats

Physiological Reports, Volume 14, Issue 11, June 2026.
Evaluation of cardiovascular parameters and renal mediators during the development of arterial hypertension in male DOCA‐Salt rats. Abstract Although renal dysfunction is present in arterial hypertension, the mechanisms underlying renal glomerular and tubular alterations remain incompletely understood.
Edina Da Luz Abreu, Rafael S. Carvalhal, Ana Caroline Marreiros, Stephanie F. Gerolin, Laura Barroso F. Oliveira, Maria Eduarda Abreu‐Cunha, Diogo B. Peruchetti, Cristiane D. Gil, Cássia T. Bergamaschi, Ruy R. Campos   +9 more
wiley   +1 more source

Renal denervation in an animal model of diabetes and hypertension: Impact on the autonomic nervous system and nephropathy

Cardiovascular Diabetology, 2011
Background The effects of renal denervation on cardiovascular reflexes and markers of nephropathy in diabetic-hypertensive rats have not yet been explored.
Machado Ubiratan F, Okamoto Maristela, Souza Martina S, Azambuja Felipe, Leguisamo Natalia M, Casali Karina R, Dias Lucinara D, Irigoyen Maria, Schaan Beatriz D   +8 more
doaj   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, Volume 13, Issue 5, Page 1078-1083, May 2026.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source