Results 201 to 210 of about 1,206,636 (268)

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Short-term mortality prediction based on biochemical blood markers in azotemic cattle with renal disease. [PDF]

J Vet Intern Med
De Campos C, Cote E, Gonçalves-Brandão M, Lucas MN, Corbière F, Trumel C, Schelcher F.   +6 more
europepmc   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Cingulate Gradient Dysfunction in End-Stage Renal Disease: Associations With Clinical Phenotypes and Exploratory Transcriptomic Signatures. [PDF]

CNS Neurosci Ther
Li P, Mu JY, Zhu XY, Yuan HJ, Luo ZY, Zhu QG, Niu X, Feng XL, Han Y, Ge T, Wang CX, Wang W, Zhang M.   +12 more
europepmc   +1 more source

Correction to "Methotrexate-Induced Drug Hypersensitivity Syndrome Presenting With Acute Cerebral Infarction in End-Stage Renal Disease: A Case Report". [PDF]

Clin Case Rep
europepmc   +1 more source

Long-Term Outcomes of Leadless Pacemaker vs. Transvenous Pacemaker in End-Stage Renal Disease. [PDF]

J Cardiovasc Electrophysiol
Agarwal S, Patel HP, Patil S, Gupta A, Patel D, Asad ZUA, Munir MB, Sugrue A, Tan NY, Munoz FD, Cha YM, DeSimone CV, Deshmukh A.   +12 more
europepmc   +1 more source

From assistant to collaborator: A systematic review of the evolution of artificial intelligence in end-stage renal disease care and management. [PDF]

PLOS Digit Health
Wang M, Hong C, Huang Z, Shao F, Gu Y.
europepmc   +1 more source

Does receiving red yeast rice prescriptions (LipoCol Forte®) increase the risk of end-stage renal disease or not? A retrospective cohort study. [PDF]

PLoS One
Chang CC, Lam F, Yeh CC, Lin JG, Chen TL, Liao CC.   +5 more
europepmc   +1 more source

Clinical Characteristics and Influencing Factors of Cognitive Impairment in Patients With End-Stage Renal Disease Undergoing Maintenance Haemodialysis. [PDF]

Actas Esp Psiquiatr
Jiang X, Miao X.
europepmc   +1 more source