Results 61 to 70 of about 1,352,945 (362)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Renal function and physical fitness after 12-mo supervised training in kidney transplant recipients [PDF]

, 2018
To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care ...
Andreoli, Lucia, Anedda, Alberto, Angelini, Maria Laura, Brugin, Erica, Di Michele, Rocco, Ermolao, Andrea, Galanti, Giorgio, La Manna, Gaetano, Merlo, Laura, Merni, Franco, Mosconi, Giovanni, Nanni Costa, Alessandro, Roi, GIULIO SERGIO, Sarto, Patrizio, Sella, Gianluigi, Sgarzi, Sergio, Stancari, Michele, Stefani, Laura, Storani, Daniela, Todeschini, Paola, Totti, Valentina, Trerotola, Manuela, Tripi, Ferdinando   +22 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Renal fibrosis in feline chronic kidney disease: known mediators and mechanisms of injury [PDF]

, 2015
Chronic kidney disease (CKD) is a common medical condition of ageing cats. In most cases the underlying aetiology is unknown, but the most frequently reported pathological diagnosis is renal tubulointerstitial fibrosis.
Elliott, J, Jepson, R E, Lawson, J S, Syme, H M, Wheeler-Jones, C P D   +4 more
core   +1 more source

Patient experiences with self-monitoring renal function after renal transplantation: results from a single-center prospective pilot study

Patient Preference and Adherence, 2015
Céline L van Lint,1 Paul JM van der Boog,1 Wenxin Wang,2,3 Willem-Paul Brinkman,2 Ton JM Rövekamp,3 Mark A Neerincx,2 Ton J Rabelink,1 Sandra van Dijk1,4 1Department of Nephrology, Leiden University Medical Centre (LUMC), Leiden, 2Faculty of
van Lint CL, van der Boog PJM, Wang W, Brinkman WP, Rövekamp TJM, Neerincx MA, Rabelink TJ, van Dijk S   +7 more
doaj  

Presence of transient hydronephrosis immediately after surgery has a limited influence on renal function 1 year after ileal neobladder construction

BMC Urology, 2017
Background Urinary tract obstruction and postoperative hydronephrosis are risk factor for renal function deterioration after orthotopic ileal neobladder construction.
Takuma Narita, Shingo Hatakeyama, Takuya Koie, Shogo Hosogoe, Teppei Matsumoto, Osamu Soma, Hayato Yamamoto, Tohru Yoneyama, Yuki Tobisawa, Takahiro Yoneyama, Yasuhiro Hashimoto, Chikara Ohyama   +11 more
doaj   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Recovery of native renal function in patients with hepatorenal syndrome following combined liver and kidney transplant with Mercaptoacetyltriglycine-3 renogram: Developing a methodology

World Journal of Nuclear Medicine, 2016
Many patients with hepatorenal syndrome (HRS) end up receiving a combined liver and kidney transplant (CKLT) with preservation of native kidneys, specially type 1 HRS since is characterizes by a very rapid deterioration of renal function.
Carina Aparici, Sukhkarn Bains, David Carlson, Jesse Qian, Douglas Liou, David Wojciechowski, Jacob Werner, Sana Khan, Cameron Kroll, Manreet Sandhu, Nhan Nguyen, Randall Hawkins   +11 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Alemtuzumab preconditioning with tacrolimus monotherapy - The impact of serial monitoring for donor-specific antibody [PDF]

, 2008
BACKGROUND. Antibody preconditioning with tacrolimus monotherapy has allowed many renal allograft recipients to be maintained on spaced weaning. METHODS.
Adriana Zeevi, Alin L. Girnita, Amadeo Marcos, Amit Basu, Calne, Deanna M. Blisard, Edward A. Gray, Girnita, Henkie P. Tan, Kirk, Knechtle, Kowalski, Liise K. Kayler, Mao, Meier-Kriesche, Mizutani, Montgomery, Ngoc L. Thai, Parmjeet S. Randhawa, Pascual, Pei, Ron Shapiro, Shapiro, Shapiro, Shapiro, Starzl, Stuart, Tan, Thomas E. Starzl, Waldmann   +29 more
core   +1 more source