Results 81 to 90 of about 1,236,008 (363)

Pathfinder cells provide a novel therapeutic intervention for acute kidney injury [PDF]

, 2013
Pathfinder cells (PCs) are a novel class of adult-derived cells that facilitate functional repair of host tissue. We used rat PCs to demonstrate that they enable the functional mitigation of ischemia reperfusion (I/R) injury in a mouse model of renal ...
Alan MacIntyre, Alasdair I. MacDonald, Christian Koppelstaetter, David Russell, Herrera MB, Iwatani H, Kathrin Eller, Liane M. McGlynn, Megyesi J, Paul G. Shiels, R.W. Davies, Thakar CV   +11 more
core   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Predictive abilities of cardiovascular biomarkers to rapid decline of renal function in Chinese community-dwelling population: a 5-year prospective analysis

BMC Nephrology, 2017
Background Predictive abilities of cardiovascular biomarkers to renal function decline are more significant in Chinese community-dwelling population without glomerular filtration rate (GFR) below 60 ml/min/1.73m2, and long-term prospective study is an ...
Shihui Fu, Chunling Liu, Leiming Luo, Ping Ye   +3 more
doaj   +1 more source

Treatment of atherosclerotic renovascular hypertension: review of observational studies and a meta-analysis of randomized clinical trials. [PDF]

, 2015
open9Atherosclerotic renal artery stenosis can cause ischaemic nephropathy and arterial hypertension. We herein review the observational and randomized clinical trials (RCTs) comparing medical and endovascular treatment for control of hypertension and ...
Caielli, P, Calò, Frigo, Anna Chiara, Maiolino, G, Miotto, Diego, Pengo, Mf, Rossi, Gianpaolo, Rossitto, G, Seccia, Teresa Maria   +8 more
core   +1 more source

Revascularization as a treatment to improve renal function

International Journal of Nephrology and Renovascular Disease, 2014
Helen V Alderson, James P Ritchie, Philip A Kalra The University of Manchester, Manchester Academic Health Sciences Centre, Vascular Research Group, Department of Renal Medicine, Salford Royal NHS Foundation Trust, Salford, UK Abstract: An aging ...
Alderson HV, Ritchie JP, Kalra PA
doaj  

Trends and predictors of changes in renal function after radical nephrectomy for renal tumours

BMC Nephrology
Background Chronic kidney disease (CKD) is a common postoperative complication in patients who undergo radical nephrectomy for renal tumours. However, the factors influencing long-term renal function require further investigation.
Yongchao Yan, Yunbo Liu, Bin Li, Shang Xu, Haotian Du, Xinning Wang, Yanjiang Li   +6 more
doaj   +1 more source

Renal function, uraemia and early arteriovenous fistula failure [PDF]

, 2014
Background Guidance varies regarding the optimal timing of arteriovenous fistula (AVF) creation. The aim of this study was to evaluate the association between uraemia, haemodialysis and early AVF failure.
Aitken, Emma, Coats, Paul, Jackson, Andrew, Kingsmore, David, Kong, Chia   +4 more
core   +2 more sources

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

Effect of Percutaneous Nephrostomy in Late Stage Cervical Cancer's Survival with Impaired Renal Function [PDF]

, 2016
Objective: explore the association between percutaneous nephrostomy and survival of patients with advanced cervical cancer accompanied by renal impairment.Materials and Methods: Retrospective cohort, with 70 samples taken with consecutive sampling.
Gunawan, A. (Ali), Rasjidi, I. (Imam), Susanto, C. (Christine)   +2 more
core  

Alemtuzumab preconditioning with tacrolimus monotherapy - The impact of serial monitoring for donor-specific antibody [PDF]

, 2008
BACKGROUND. Antibody preconditioning with tacrolimus monotherapy has allowed many renal allograft recipients to be maintained on spaced weaning. METHODS.
Adriana Zeevi, Alin L. Girnita, Amadeo Marcos, Amit Basu, Calne, Deanna M. Blisard, Edward A. Gray, Girnita, Henkie P. Tan, Kirk, Knechtle, Kowalski, Liise K. Kayler, Mao, Meier-Kriesche, Mizutani, Montgomery, Ngoc L. Thai, Parmjeet S. Randhawa, Pascual, Pei, Ron Shapiro, Shapiro, Shapiro, Shapiro, Starzl, Stuart, Tan, Thomas E. Starzl, Waldmann   +29 more
core   +1 more source