Results 51 to 60 of about 1,621,854 (283)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Principle and characteristics of the mapping/selective renal denervation system and its research progress in hypertension treatment

Zhongguo Linchuang Yixue
Renal denervation (RDN) as an interventional approach for treating refractory hypertension has developed a variety of ablation strategies and different energy ablation techniques. This article reviews the principles, characteristics, clinical advantages,
Li WANG, Xiaoqiang SUN, Chengzhi LU
doaj   +1 more source

Frequency-coded patterns of sympathetic vasomotor activity are differentially evoked by the paraventricular nucleus of the hypothalamus in the Goldblatt hypertension model

Frontiers in Cellular Neuroscience, 2023
IntroductionThe paraventricular nucleus of the hypothalamus (PVN) contains premotor neurons involved in the control of sympathetic vasomotor activity. It is known that the stimulation of specific areas of the PVN can lead to distinct response patterns at
Jean Faber, Maycon I. O. Milanez, Cristiano S. Simões, Ruy R. Campos   +3 more
doaj   +1 more source

Unique Role of Microstructure of a Bioimplant Zinc Alloy and Protein Content of Simulated Body Fluid in Corrosion and Fracture

Advanced Functional Materials, EarlyView.
BSA addition to physiological solutions enhances resistance of a Zn alloy to stress corrosion cracking (SCC) but reduces its corrosion resistance. Extended surface characterization explains the contrasting influences on corrosion and SCC. Unexpectedly, the alloy suffers transgranular SCC (TGSCC), despite extensive grain boundary precipitation. Thorough
RK Singh Raman, Syed Hussain Wajahat, Saad Al‐Saadi, Robin E. Schäublin, Peng Zeng, Solomon Ansah, Jixing Lin, Xian Tong, Cuie Wen, Jörg F. Löffler   +9 more
wiley   +1 more source

CIDP, myasthenia gravis, and membranous glomerulonephritis – three autoimmune disorders in one patient: a case report

BMC Neurology, 2018
Background We present a patient fulfilling the electrophysiological criteria for definite chronic inflammatory demyelinating polyneuropathy (CIDP), antibody-positive myasthenia gravis (MG), and membranous glomerulonephritis (MGN) confirmed by biopsy.
Saskia Bolz, Andreas Totzeck, Kerstin Amann, Mark Stettner, Christoph Kleinschnitz, Tim Hagenacker   +5 more
doaj   +1 more source

Hypertension in chronic kidney disease: What lies behind the scene

Frontiers in Pharmacology, 2022
Hypertension is a frequent condition encountered during kidney disease development and a leading cause in its progression. Hallmark factors contributing to hypertension constitute a complexity of events that progress chronic kidney disease (CKD) into end-
Omar Z. Ameer, Omar Z. Ameer
doaj   +1 more source

[The renal nerve and cardiovascular responses to renal receptor stimulation with veratrine in dogs].

Nihon Jinzo Gakkai shi, 1991
Renal nerve and cardiovascular effects of intrarenal veratrine (Ver) were investigated using the cross-perfused kidney preparations of anesthetized dogs. Ver (1 and 3 micrograms/kg), injected as a bolus, elicited increases in arterial blood pressure (ABP), heart rate (HR) and renal efferent nerve activity (RENA).
HIRAO, SHU, TOMOMATSU, EIJI, OHBA, HIDEICHI, SUZUKI, KAZUFUMI, YAGI, SHIGERU   +4 more
openaire   +2 more sources

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Does electrical stimulation in the lower urinary tract increase urine production? A randomised comparative proof-of-concept study in healthy volunteers.

PLoS ONE, 2019
Trial designDuring electrical stimulation in the lower urinary tract for the purpose of current perception threshold and sensory evoked potential recording, we observed that bladder volume increased rapidly.
Stéphanie van der Lely, Martina D Liechti, Werner L Popp, Melanie R Schmidhalter, Thomas M Kessler, Ulrich Mehnert   +5 more
doaj   +1 more source

Augmented Respiratory–Sympathetic Coupling and Hemodynamic Response to Acute Mild Hypoxia in Female Rodents With Chronic Kidney Disease

Frontiers in Physiology, 2021
Carotid body feedback and hypoxia may serve to enhance respiratory–sympathetic nerve coupling (respSNA) and act as a driver of increased blood pressure.
Manash Saha, Manash Saha, Manash Saha, Qi-Jian Sun, Cara M. Hildreth, Peter G. R. Burke, Peter G. R. Burke, Jacqueline K. Phillips   +7 more
doaj   +1 more source