Results 101 to 110 of about 321,443 (350)
Segment-specific expression of 2P domain potassium channel genes in human nephron. [PDF]
BackgroundThe 2P domain potassium (K2P) channels are a recently discovered ion channel superfamily. Structurally, K2P channels are distinguished by the presence of two pore forming loops within one channel subunit. Functionally, they are characterized by
Bockenhauer, Detlef+3 more
core +1 more source
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim+8 more
wiley +1 more source
Prognostic robustness of serum creatinine based AKI definitions in patients with sepsis: a prospective cohort study [PDF]
Background: It is unclear how modifications in the way to calculate serum creatinine (sCr) increase and in the cut-off value applied, influences the prognostic value of Acute Kidney Injury (AKI).
Dhondt, Annemieke+4 more
core +2 more sources
Metal Nanoclusters for Cancer Imaging and Treatment
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu+5 more
wiley +1 more source
Identification of Urinary Activin A as a Novel Biomarker Reflecting the Severity of Acute Kidney Injury [PDF]
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Takahashi, Shunsuke+2 more
core
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
PHYSIOLOGICAL AND PATHOLOGICAL EFFECTS OF SEVERE EXERTION (THE MARATHON RACE) ON THE CIRCULATORY AND RENAL SYSTEMS [PDF]
Joseph H. Barach
openalex +1 more source
Sex differences are a complex and crucial variable in developing and progressing metabolic and cardiovascular disease pathophysiology and clinical outcomes.
Lucy C. Taylor+4 more
doaj +1 more source
Editorial: Sex differences in renal physiology. [PDF]
Singh P, Dutta SR, Sullivan JC.
europepmc +1 more source
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John+5 more
wiley +1 more source