Results 31 to 40 of about 538,702 (314)

Drug Dosing Considerations in Critically Ill Patients Receiving Continuous Renal Replacement Therapy

Pharmacy, 2020
Acute kidney injury is very common in critically ill patients requiring renal replacement therapy. Despite the advancement in medicine, the mortality rate from septic shock can be as high as 60%.
S. Jang, Sergio Infante, Amir Abdi Pour
semanticscholar   +1 more source

A Guide to Understanding Antimicrobial Drug Dosing in Critically Ill Patients on Renal Replacement Therapy

Antimicrobial Agents and Chemotherapy, 2019
A careful management of antimicrobials is essential in the critically ill with acute kidney injury, especially if renal replacement therapy is required. Acute kidney injury may lead per se to clinically significant modifications of drugs’ pharmacokinetic
V. Pistolesi, S. Morabito, F. Di Mario, G. Regolisti, Chiara Cantarelli, E. Fiaccadori   +5 more
semanticscholar   +1 more source

Antioxidant Supplementation in Renal Replacement Therapy Patients: Is There Evidence?

Oxidative Medicine and Cellular Longevity, 2019
The disruption of balance between production of reactive oxygen species and antioxidant systems in favor of the oxidants is termed oxidative stress (OS).
V. Liakopoulos, S. Roumeliotis, A. Bozikas, T. Eleftheriadis, E. Dounousi   +4 more
semanticscholar   +1 more source

Exploring challenges and considerations while providing hemodialysis to pediatric, elderly, and pregnant cases: A narrative review of globally published literature

Clinical Epidemiology and Global Health
Background: Hemodialysis patients have unique physiological characteristics that necessitate specialized care during the treatment. As the prevalence of kidney disease continues to rise, the importance of addressing the unique needs of these patient ...
Megha Nagaraj Nayak, Veena Natti Krishna
doaj   +1 more source

Biomarkers for prediction of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis

Intensive Care Medicine, 2018
PurposeAcute kidney injury (AKI) frequently occurs in critically ill patients and often precipitates use of renal replacement therapy (RRT). However, the ideal circumstances for whether and when to start RRT remain unclear.
S. Klein, A. Brandtner, G. Lehner, H. Ulmer, S. Bagshaw, C. Wiedermann, M. Joannidis   +6 more
semanticscholar   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

COVID-19 and Renal Failure: Challenges in the Delivery of Renal Replacement Therapy

Journal of Clinical Medicine Research, 2020
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first officially reported in December 2019 in Wuhan City, Hubei province, China, and has since lead to a pandemic.
Sreedhar Adapa, N. Aeddula, V. Konala, A. Chenna, Srikanth Naramala, B. Madhira, Vijay Gayam, Mamtha Balla, Vijayadershan Muppidi, Subhasish Bose   +9 more
semanticscholar   +1 more source

Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel, Santiago Pérez‐Hoyos, Aroa Soriano, Ana Coma, Amalia Varo, Raquel Hladun, Gabriela Guillén, Soraya Mico, Marta Garrido, Lourdes Rubio, Alba Rubio‐San‐Simón, Ana Minguez, Ricardo López‐Almaraz, Laura Illade, Miguel F. Segura, Lucas Moreno   +15 more
wiley   +1 more source

Delaying treatment for peritonitis could be related to longer hospitalization in patients on peritoneal dialysis

Renal Replacement Therapy
Background When peritoneal dialysis (PD)-related peritonitis occurs in PD patients, diagnostic and therapeutic approaches should be started as soon as possible.
Yusaku Koshitori, Nami Takai, Yoshihito Isomura, Tetsuaki Hiramatsu, Yasuhiro Suzuki, Hangsoo Kim, Sosuke Fukui, Masashi Mizuno   +7 more
doaj   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source