Results 41 to 50 of about 3,286,893 (204)

Acute kidney injury in a cardiac ICU in a middle-income country: risk factors and outcomes from Thailand

open access: yesBMC Nephrology
Background Acute kidney injury (AKI) is associated with significant morbidity and mortality in critically ill patients. However, data on AKI in coronary care units (CCU) remain limited, particularly in low- and middle-income countries.
Supassara Nimkulrat   +6 more
doaj   +1 more source

Continuous renal replacement therapy: Opinions and evidence

open access: yes, 2002
Continuous arteriovenous haemofiltration (CAVH) is the first example of continuous renal replacement therapy (CRRT). CAVH was first applied for the treatment of diuretic unresponsive fluid overload.
Ronco C, Bellomo R, Kellum JA
core   +1 more source

Timing of initiation of renal-replacement therapy in acute kidney injury [PDF]

open access: yes, 2020
Background Acute kidney injury is common in critically ill patients, many of whom receive renal-replacement therapy. However, the most effective timing for the initiation of such therapy remains uncertain. Methods We conducted a multinational, randomized,
McAuley, Daniel F   +57 more
core   +2 more sources

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Potential sex differences in longitudinal chest-radiograph signatures preceding heart failure in peritoneal dialysis patients

open access: yesRenal Replacement Therapy
Background Heart failure (HF) is a leading cause of morbidity and mortality among individuals with kidney failure with replacement therapy (KFRT). Although biological sex influences cardiovascular disease, it remains unclear whether and how longitudinal ...
Reiko Muto   +6 more
doaj   +1 more source

Differences between physicians in the likelihood of referral and acceptance of elderly patients for dialysis-influence of age and comorbidity [PDF]

open access: yes, 2007
BACKGROUND: Incidence of dialysis in elderly patients in the Netherlands is low compared to other countries. This study aims to assess the impact of patients' age and comorbidity on the likelihood of referral and acceptance of patients for dialysis and ...
Gansevoort, R.T.   +9 more
core   +2 more sources

Continuous Renal Replacement Therapy in Critically Ill Children

open access: yes, 2022
Continuous renal replacement therapy is an extracorporeal blood purification therapy that aims to support kidney and other organ functions over an extended period.
Demet Demirkol, Demirkol, Demet
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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