Results 91 to 100 of about 259,832 (291)
Advanced Science, EarlyView.Schematic illustration of the synthesis protocol for Fe‐SH@Fn, an AML‐targeted nanoplatform engineered to co‐deliver shikonin (SH) and Fe3+, synergistically boosting antitumor immunity via ferroptosis induction and immunogenic cell death (ICD). ABSTRACT Acute myeloid leukemia (AML) remains a therapeutic challenge due to its low immunogenicity and ...
Shangqin Yang +9 more
wiley +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
POS-338 GASTRO-INTESTINAL ANGIODYSPLASIA IN PATIENTS WITH CHRONIC KIDNEY DISEASE
Kidney International Reports, 2021 S. MEKKI +7 more
doaj +1 more source
Transplantation & Vascular Surgery: Renal Transplantation & Vascular Surgery III (MP76) [PDF]
, 2019 openalex +1 more source
Anaesthetic challenges in the management of renal transplant recipients - An institutional review.
, 2023 Salman Shazad +7 more
openalex +2 more sources
Advanced Science, EarlyView.This study emphasizes the role of the Mapk13‐Tcf1‐Slc7a5‐methionine metabolism axis in stem‐like CD4+ T cells. Moreover, it uncovers the mechanism through which limiting one‐carbon metabolism in CD4+ stem‐like T cells suppresses the tide of chronic allograft vasculopathy, offering potential targets to promote long‐term graft survival.
Wang Yi +8 more
wiley +1 more source
European Renal Association – European Dialysis and Transplant Association
, 2015 openalex +1 more source
Efficacy and safety of low-dose valganciclovir prophylaxis among renal transplant recipients
, 2020 Emel İşiktaş Sayilar, İhsan Ergün
openalex +2 more sources
Advanced Science, EarlyView.We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza +19 more
wiley +1 more source