Results 61 to 70 of about 721,252 (305)

Organ transplantation from deceased donors with cancer: is it safe? [PDF]

open access: yes, 2011
Michael A Nalesnik1, Michael G Ison21Division of Transplantation and Hepatic Pathology, Department of Pathology, University of Pittsburgh Medical Center, Pittsburg, PA, USA; 2Divisions of Infectious Diseases and Organ Transplantation, Northwestern ...
Ison,, Nalesnik, Michael
core   +2 more sources

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

The Benefit and Harm of an Implantable Cardiac Defibrillator in a Patient with Heart Failure: A Case Report and Literature Review

open access: yesReports
Background and Clinical Significance: Infective endocarditis (IE) in patients with cardiac implantable electronic devices (CIED-IE) is a severe condition with high mortality and increasing prevalence.
Mihai Grigore   +4 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Computed Tomographic Characteristics of Feline Renal Cell Carcinoma and Renal Lymphoma: A Comparative Analysis

open access: yesVeterinary Sciences
This retrospective, multicenter study aimed to identify key computed tomography (CT) features that differentiate renal cell carcinoma (RCC) from lymphoma, the two most common feline renal neoplasms. CT images from 25 cats with renal tumors (15 RCC and 10
Choye Shin   +11 more
doaj   +1 more source

Circular RNAs in Clear Cell Renal Cell Carcinoma: Their Microarray-Based Identification, Analytical Validation, and Potential Use in a Clinico-Genomic Model to Improve Prognostic Accuracy [PDF]

open access: yes, 2019
Circular RNAs (circRNAs) may act as novel cancer biomarkers. However, a genome-wide evaluation of circRNAs in clear cell renal cell carcinoma (ccRCC) has yet to be conducted. Therefore, the objective of this study was to identify and validate circRNAs in
Erbersdobler, Andreas   +9 more
core   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Application of low‐dose CT to the creation of 3D‐printed kidney and perinephric tissue models for laparoscopic nephrectomy

open access: yesCancer Medicine, 2021
Purpose The aim of this study was to explore the feasibility of 3D printing of kidney and perinephric fat based on low‐dose CT technology. Patients and Methods A total of 184 patients with stage T1 complex renal tumors who underwent laparoscopic ...
Guan Li   +7 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Evaluation of the MR and pathology characteristics immediately following percutaneous MR-guided microwave ablation in a rabbit kidney VX2 tumor implantation model

open access: yesInternational Journal of Hyperthermia, 2019
Purpose: This study aimed to evaluate the immediate efficacy of magnetic resonance (MR)-guided microwave ablation (MWA) in rabbit kidneys implanted with VX2 tumors. Materials and methods: MR-guided MWA was performed in eight VX2 tumor-bearing rabbits. MR
Hao Li, Zhengyu Lin, Jie Chen, Rui Guo
doaj   +1 more source

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