Results 31 to 40 of about 553,202 (296)

Erőszak és társadalmi rend

Köz-gazdaság, 2020
A Harvard Egyetemen működő Kvantitatív Társadalomtudományi Intézet minden évben megrendezi a „Találkozás a szerzőkkel” című szimpóziumot, amelyen neves társadalomkutatók szakmai vitára bocsátják készülő könyvük kéziratát. 2007 októberében Douglass North,
JÓZSEF MISZ
doaj  

Algebraic cycles on a very special EPW sextic

, 2017
Motivated by the Beauville-Voisin conjecture about Chow rings of powers of $K3$ surfaces, we consider a similar conjecture for Chow rings of powers of EPW sextics. We prove part of this conjecture for the very special EPW sextic studied by Donten-Bury et
Laterveer, Robert
core   +1 more source

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

Advanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi, Ming‐yang Wu, Jin‐quan Liu, Cuicui Tian, Li Ma, Xue‐mei Zhou, Ze‐Hao Sun, Zhi‐yong Xu, Run‐dong Zhang, Shan‐yuan Ye, Li‐ming Huang, Yan Wang, Jing‐shu Xiong, Wen‐bo Bu, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +16 more
wiley   +1 more source

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

Hepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu, Xiude Fan, Megan R. McMullen, Tatsunori Miyata, Adam Kim, Vai Pathak, Jianguo Wu, Le Z. Day, Josiah E. Hardesty, Nicole Welch, Jaividhya Dasarathy, Daniela S. Allende, Arthur J. McCullough, Jon M. Jacobs, Daniel M. Rotroff, Srinivasan Dasarathy, Laura E. Nagy   +16 more
wiley   +1 more source

Az Országos Idegenrendészeti Főigazgatóság megalakulása

Belügyi Szemle, 2020
A Bevándorlási és Menekültügyi Hivatal (BMH) – korábban Bevándorlási és Állampolgársági Hivatal – 2019. július 1-jétől rendvédelmi feladatokat ellátó szervvé alakult át, és Országos Idegenrendészeti Főigazgatóság (OIF) néven folytatta tovább működését ...
Zsuzsanna Hornyik
doaj   +1 more source

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Adaptive self-management of teams of autonomous vehicles [PDF]

, 2008
Unmanned Autonomous Vehicles (UAVs) are increasingly deployed for missions that are deemed dangerous or impractical to perform by humans in many military and disaster scenarios.
Asmare, E, Dulay, N, Gopalan, A, Lupu, E, Sloman, M   +4 more
core   +1 more source

Visualization of Endosomal Escape of Intracellularly Delivered Protein With Unexpected Photochemical Internalization of Trypan Blue

Advanced Science, EarlyView.
TB, a conventional cell viability dye, acts as both a fluorescence modulator (quenching GFP fluorescence upon protein binding and recovering it upon release) and a photosensitizer that triggers endosomal escape via photochemical internalization (PCI) under 590 nm light.
Zhongqi Yao, Zhan Shi, Peng Hu, Changping Wang, Hui Wang   +4 more
wiley   +1 more source

The Role of Collective Neutrino Flavor Oscillations in Core-Collapse Supernova Shock Revival [PDF]

, 2012
We explore the effects of collective neutrino flavor oscillations due to neutrino-neutrino interactions on the neutrino heating behind a stalled core-collapse supernova shock.
A. Burrows, B. Pontecorvo, Basudeb Dasgupta, Christian D. Ott, Evan P. O’Connor, G. S. Bisnovatyi-Kogan, S. D. Cohen, S. P. Mikheev, S. W. Bruenn, Y. Suwa   +9 more
core   +2 more sources

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source