Results 51 to 60 of about 1,233 (214)

8‐Oxoguanine Modified CircMTUS1 Drives PABPC1 Phase Separation to Promote Gastric Cancer Progression and Cisplatin Resistance via Autophagy

Advanced Science, EarlyView.
ABSTRACT Gastric cancer (GC) is a major global health concern, as its prevention and treatment remain significant challenges. The 8‐oxoguanine (o8G) modification of circRNAs, alongside their capacity to orchestrate liquid‐liquid phase separation (LLPS) and autophagy, plays a pivotal role in driving tumor progression and determining therapeutic outcomes.
Lei Peng, Lurong Li, Zhenghui Zhu, Chenyang Li, Huaiming Sang, Guoxin Zhang, Xuan Li, Yini Dang, Yuanyuan Li   +8 more
wiley   +1 more source

Skit i traditionerna

Barnelitterært Forskningstidsskrift, 2020
Under efterkrigstiden sker en genomgående förändring av ungdomstiden och idag framstår 1950-talet som en brytpunkt, där såväl ungdomsskildringen, ungdomsboken som synen på ungdomen och normerna för vuxenblivandet transformeras.
Lydia Wistisen
doaj   +1 more source

Strategy of Triple‐Gradient in Binary Pixels for Flexible Pressure Sensing with High Sensitivity and Wide‐Range Linearity

Advanced Science, EarlyView.
A flexible pressure sensor with triple‐gradient design of conductivity, modulus, and dimension in binary micro‐dome pixels is proposed. Based on precisely‐designed CNT/PDMS matrix, the device exhibits a linear sensitivity of 974.1 kPa−1 across range up to 1.8 MPa (R2 > 0.99), offering an effective strategy for potential applications in healthcare ...
Yifan Liu, Xiao Xu, Fengming Hu, Yuanzhe Liang, Zidong Yin, Biao Qi, Ruolin Liu, Ziyi Dai, Jianyi Luo, Bingpu Zhou   +9 more
wiley   +1 more source

Quai de l’Équinoxe

Babel: Littératures Plurielles, 2014
Philippe Le Guillou rend hommage à Montherlant dont l’œuvre a incarné pour lui à la fois un appel à étreindre la beauté du monde, et une exigence radicale, éthique et romaine.
Philippe Le Guillou
doaj   +1 more source

WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

Advanced Science, EarlyView.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng, Zijie Ye, Manna Zheng, Jing Pan, Tianbao Tan, Jiliang Yang, Jiahao Li, Zhang Zhao, Tianzhu Long, Liyu Zhang, Gautam Sethi, Tianyou Yang, Chao Hu, Yan Zou   +13 more
wiley   +1 more source

Interjú a Dr. Kertész Imre-díjjal kitüntetett Fenyvesi Csaba professzor úrral

Belügyi Szemle
A tanulmány egyedülálló életút és szakmai teljesítmény bemutatásán keresztül ad átfogó képet Fenyvesi Csaba professzor úr munkásságáról, aki a bűnüldözés gyakorlati tapasztalatait és a kriminalisztika tudományos eredményeit ötvözi.
Csaba Szabó
doaj   +1 more source

La fin de la guerre d’Indochine (1953-1954) vue par L’Humanité

Cahiers d’histoire, 2003
Cet article retrace la manière dont l’organe central du Parti communiste français rend compte de la guerre d’Indochine et plus particulièrement des dernières années « françaises » de la guerre.
Alain Ruscio
doaj   +1 more source

Maximizing Nanoscale Disorder in Block Copolymers for Orientation‐Independent SERS Platform Toward Non‐Invasive Diagnostics

Advanced Science, EarlyView.
Maximizing Nanoscale Disorder in Block Copolymers for Orientation‐Independent SERS Platform toward Non‐Invasive Diagnostics is a nature‐inspired strategy that engineers controlled randomness within block copolymer lamellae to achieve optical isotropy without compromising nanoscale periodicity.
Jin Man Kim, Wonsik Kim, Wansun Kim, Yeon‐Hee Kim, Samjin Choi, Jang Hwan Kim, Hyeong Min Jin   +6 more
wiley   +1 more source

„Egység a sokféleségben”. A decentralizáció folyamata Indonéziában az „új rend” bukása után

Tér és Társadalom, 2013
Elemzők szerint Indonéziában mind a mai napig a decentralizált kormányzás a leghatékonyabb struktúra az ország heterogenitása, földrajza és mérete miatt.
Szarka Evelin
doaj   +1 more source

RGS16 Aggravates Hepatic Ischemia‐Reperfusion Injury via Hepatocyte‐Intrinsic Apoptosis/Inflammation & Neutrophil Recruitment/NETosis

Advanced Science, EarlyView.
RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...
Xinglong Li, Zhanzhi Meng, Hongjun Yu, Yongliang Hua, Zihao Li, Bing Yin, Baolin Qian, Zhongyu Li, Yongzhi Zhou, Zhigang Feng, Shounan Lu, Shanjia Ke, Miaoyu Bai, Yao Fu, Wei Tang, Natalia V. Belosludtseva, Yong Ma   +16 more
wiley   +1 more source