Results 91 to 100 of about 182,790 (356)
Developing serious games for cultural heritage: a state-of-the-art review [PDF]
Although the widespread use of gaming for leisure purposes has been well documented, the use of games to support cultural heritage purposes, such as historical teaching and learning, or for enhancing museum visits, has been less well considered.
A Lerner +60 more
core +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
HOLOGRAPHICS: Combining Holograms with Interactive Computer Graphics [PDF]
Among all imaging techniques that have been invented throughout the last decades, computer graphics is one of the most successful tools today. Many areas in science, entertainment, education, and engineering would be unimaginable without the aid of 2D or
Bimber, Oliver (Prof. Dr.)
core
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
SHADER METAMODEL AS A COMPONENT OF AN INTERACTIVE APPLICATION ARCHITECTURE
This article introduces the rendering metamodel as an architecture basis for complicated graphi-cal applications. The model separates abstract logical and algorithmic approaches used in modern computer graphics theory from problems of computational ...
V. Kazantsava +2 more
doaj
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A Sort-Last Rendering System over an Optical Backplane [PDF]
Sort-Last is a computer graphics technique for rendering extremely large data sets on clusters of computers. Sort-Last works by dividing the data set into even-sized chunks for parallel rendering and then composing the images to form the final result ...
Yasuhiro Kirihata +3 more
doaj
Network based medical data computing and collaborative visualization have been commonly used in remote medicine and distributed diagnosis, where visualizing 3D medical data on web browsers and sharing medical information on internet are critically ...
Qi Zhang
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Light field image processing : overview and research issues [PDF]
Light field (LF) imaging first appeared in the computer graphics community with the goal of photorealistic 3D rendering [1]. Motivated by a variety of potential applications in various domains (e.g., computational photography, augmented reality, light ...
Farrugia, Reuben A. +1 more
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