Results 41 to 50 of about 520,057 (273)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
INTEGRATED RENEWAL PROCESS [PDF]
Journal of the Indonesian Mathematical Society, 2012 The marginal distribution of integrated renewal process is derived in this paper. Our approach is based on the theory of point processes, especially Poisson point processes. The results are presented in the form of Laplace transforms.
Suyono ., J.A.M. van Der Weide
openaire +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Organisasievernuwing: Die identifisering en integrasie van enkele konstrukte
SA Journal of Industrial Psychology, 1989 Organisational renewal: The identification of certain constructs. Organisations consist of interactive subsystems and processes which create a whole-forming "Gestalt".
M. L. Watkins, A. L. Barnard
doaj +1 more source
Redai dili, 2021 During the processes of stock land redevelopment, appropriate profit allocation is key to promoting the implementation of urban renewal. Meanwhile, its intricate, multi-participant interest games tends to obstruct the progress of urban renewal programs ...
Deng Maoying, Deng Cefang
doaj +1 more source
Guide To Ecocycle Mapping [PDF]
, 2016 The ecocycle tool can be used to help understand the health and renewal of your work and to identify potential traps to avoid.This tool applies research into natural ecological systems, which has shown the importance of a continuous loop of development ...
core
The Embedding Capacity of Information Flows Under Renewal Traffic
, 2011 Given two independent point processes and a certain rule for matching points between them, what is the fraction of matched points over infinitely long streams? In many application contexts, e.g., secure networking, a meaningful matching rule is that of a
He, Ting +3 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Contact process under renewals I
, 2018 Motivated by questions regarding long range percolation, we investigate a non-Markovian analogue of the Harris contact process in $\mathbb{Z}^d$: an individual is attached to each site $x \in \mathbb{Z}^d$, and it can be infected or healthy; the ...
Fontes, Luiz Renato G. +3 more
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BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source