Results 261 to 270 of about 172,424 (309)
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Cardiac Renin–Angiotensin System
American Journal of Hypertension, 1989Based on molecular, biological, biochemical, and pharmacological data, evidence is presented for a cardiac renin-angiotensin system. Using radiolabeled cRNA probes prepared from specific cDNA fragments, we were able to document renin and angiotensinogen gene expression in atria and ventricles of the rat heart by Northern blot and liquid hybridization ...
W, Linz +3 more
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Pharmacological Reviews, 1965
The major actions of this system seem to be exerted at an extracellular level even though there are strong suggestions that some intracellular effects may also be important.
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The major actions of this system seem to be exerted at an extracellular level even though there are strong suggestions that some intracellular effects may also be important.
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Tissue renin angiotensin systems
Medical Clinics of North America, 2004The RAAS is a powerful regulator of vascular tone and intravascular volume and of tissue architecture and a variety of other functions. The recent appreciation of the immunoregulatory role of angiotensin II and its possible involvement in the genesis of atherosclerosis and in plaque rupture all speak to the wide-ranging physiologic and pathophysiologic
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Medical Clinics of North America, 1987
The renin-angiotensin systems are important regulators of cardiovascular homeostasis and participate in a variety of pathological conditions. Recent advances have not only clarified the functioning of the systemic renin cascade but have also indicated the importance of the generation of angiotensin in tissues.
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The renin-angiotensin systems are important regulators of cardiovascular homeostasis and participate in a variety of pathological conditions. Recent advances have not only clarified the functioning of the systemic renin cascade but have also indicated the importance of the generation of angiotensin in tissues.
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Renin-angiotensin-aldosterone system
European Journal of Clinical Pharmacology, 1980There is increased activity of the renin, angiotensin, aldosterone (RAA) system in infancy and childhood. An inverse relationship between plasma renin, aldosterone and age has been demonstrated. In childhood hypertension due to renovascular disease or pyelonephritic scarring peripheral plasma renin is increased.
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Alternative Renin-Angiotensin System
HypertensionThe renin-angiotensin system is the most important peptide hormone system in the regulation of cardiovascular homeostasis. Its classical arm consists of the enzymes, renin, and angiotensin-converting enzyme, generating angiotensin II from angiotensinogen, which activates its AT 1 receptor, thereby increasing blood ...
Michael Bader +4 more
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2008
Over 100 years have passed since the discovery of renin as a “pressor substance” in 1898 by Robert Tigerstedt at Karolinska Institute. The 48-page publication “Niere und Kreislauf” in Skandinavisches Archiev fur Physiologie in 1898 by Tiegerstedt and Bergman detailed their meticulous approaches, even including the design of a flow meter to measure ...
L. Romayne Kurukulasuriya, James Sowers
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Over 100 years have passed since the discovery of renin as a “pressor substance” in 1898 by Robert Tigerstedt at Karolinska Institute. The 48-page publication “Niere und Kreislauf” in Skandinavisches Archiev fur Physiologie in 1898 by Tiegerstedt and Bergman detailed their meticulous approaches, even including the design of a flow meter to measure ...
L. Romayne Kurukulasuriya, James Sowers
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Ovarian Prorenin-Renin-Angiotensin System
Obstetrical & Gynecological Survey, 1987Renin is classically considered to be an enzyme that is synthesized by the kidneys and secreted into the circulation where it affects angiotensin production. We review here recent evidence that suggests the existence of an extra-renal renin system, the ovarian prorenin-renin-angiotensin system, which may be linked to reproductive function.
J, Itskovitz, J E, Sealey
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2015
The rennin-angiotensin system (RAS) regulates blood pressure, fluid volume, and sodium and potassium balance (Ferrario and Strawn 2006). Dysregulation of RAS system is implicated in cardiovascular disease – hypertension, atherosclerosis, left ventricular hypertrophy, myocardial infarction, stroke, congestive heart failure – and renal disease (reviewed ...
Michael Gralinski +2 more
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The rennin-angiotensin system (RAS) regulates blood pressure, fluid volume, and sodium and potassium balance (Ferrario and Strawn 2006). Dysregulation of RAS system is implicated in cardiovascular disease – hypertension, atherosclerosis, left ventricular hypertrophy, myocardial infarction, stroke, congestive heart failure – and renal disease (reviewed ...
Michael Gralinski +2 more
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The ovarian renin-angiotensin system
Regulatory Peptides, 1994We present a review that considers the regulation of ovarian function by the ovarian renin-angiotensin system. Evidence is presented that shows the ovarian renin-angiotensin system can regulate normal ovarian function by paracrine and intracrine mechanisms.
J. R. Pepperell +4 more
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