Results 281 to 290 of about 261,257 (360)

Effects of SGLT-2 inhibitors on renin-angiotensin-aldosterone system and their correlation with glucose metabolism in type 2 diabetes mellitus patients with hypertension: A prospective study. [PDF]

PLoS One
Wang N, Kong J, Lu Z, Cao F, Tian E, Li J, Li S, Liu S, Yue B.   +8 more
europepmc   +1 more source

Time course of acid–base regulation at high‐altitude: A century of insight

Experimental Physiology, EarlyView.
Andrew R. Steele, Jordan D. Bird, Michael M. Tymko   +2 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies.
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Licorice-Induced Pseudohyperaldosteronism Highlights an Underestimated Etiology of Hypertension. [PDF]

Kidney Int Rep
Bendjilali-Sabiani JJ, Cardinale A, Lamy A, Pouget AM, Boyer JC, Taillard V, Reboul P.   +6 more
europepmc   +1 more source

ClC‐2 Contributes to Hypotonicity‐Induced Adrenal Aldosterone Secretion

Acta Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim The zona glomerulosa (ZG) of the adrenal cortex regulates blood pressure and electrolyte homeostasis through aldosterone production. In ZG cells, potassium and angiotensin II (Ang II) trigger calcium oscillations that drive aldosterone synthesis.
Marina Volkert, Hoang An Dinh, Ute I. Scholl, Gabriel Stölting   +3 more
wiley   +1 more source

Microvillus Inclusion Disease: Successful Treatment of Severe Hyponatremia With High-Dose Fludrocortisone via a Possible Gut-Mediated Mechanism. [PDF]

ACG Case Rep J
Alsarhan A, Saffarini Z, Tzivinikos C, Bitzan M, Thalange N.   +4 more
europepmc   +1 more source

Albuminuria Predicts a Rapid Decline in Kidney Function in 2 International, Longitudinal Cohorts of Adults With Sickle Cell Anemia

American Journal of Hematology, Volume 101, Issue 2, Page 304-310, February 2026.
ABSTRACT Chronic kidney disease (CKD) is common and a major contributor to increased morbidity and early mortality in people with sickle cell anemia (SCA). Urine albumin‐to‐creatinine ratio (uACR) is recommended to identify patients with SCA‐related CKD but its utility in predicting long‐term kidney dysfunction remains unclear in this patient ...
Pablo Bartolucci, Étienne Audureau, Vincent Audard, Frédéric Galactéros, Guillaume Lettre, Charmaine Anthony, Olufolake Egbujo, Jin Han, Maria Armila Ruiz, James P. Lash, Victor R. Gordeuk, Xu Zhang, Santosh L. Saraf   +12 more
wiley   +1 more source

Physiologic profiling using plasma renin activity and aldosterone on blood pressure control among Ghanaian stroke survivors: A pilot trial. [PDF]

Equity Neurosci
Sarfo FS, Opare-Addo PA, Agbenorku M, Obese V, Adamu S, Gyamfi RA, Akassi J, Ababio H, Ampofo M, Mensah NA, Acheampong G, Ovbiagele B.   +11 more
europepmc   +1 more source

An experimental medicine protocol for exploring the haemodynamic effects of dual agonism at the glucagon‐like peptide‐1 and glucagon receptor in healthy subjects

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 579-588, February 2026.
Aims Glucagon‐like peptide‐1 (GLP‐1) and glucagon dual receptor agonists are in clinical development for a range of metabolic conditions, including type 2 diabetes and obesity. The cardiovascular actions at these receptors are well studied, but less is known about their combination.
James Goodman, Victoria E. Parker, Carmel M. McEniery, Giovanni Di Stefano, Annette Hubsch, Evangelia Vamvaka, Jo Helmy, Fotini Kaloyirou, Navazh Jalaludeen, Peter Barker, Lutz Jermutus, Joseph Cheriyan, Philip Ambery, Ian B. Wilkinson   +13 more
wiley   +1 more source

Adrenalectomy as a Treatment Option for Primary Aldosteronism in the Era of Robotic-Assisted Surgeries-Is It Time to Use It More Often? [PDF]

J Clin Med
Raz O, Nakash Niddam N, Atamna F, Simonovsky A, Litvin S, Leonov Polak M, Leiba A, Golomb D.   +7 more
europepmc   +1 more source