Results 31 to 40 of about 293,558 (293)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Global and Russian M&A markets analysis: trends, drivers, deal success
Вестник университета, 2020 M&A are still relevant and discussing according to global and Russian M&A statistics (value and count) and Management Tools & Trends survey, conducting by Bain & Company since 1993.
M. Yu. Katalkina
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Executive Reorganization: Report to the Montana Legislative Assembly [PDF]
, 1970 This historically-important document, the 300-page “Report to the Montana Legislative Assembly from the Montana Commission on Executive Reorganization (December 1970)” was the product of 1½ years of activity of the Commission and its staff.
Commission on Executive Reorganization, Montana
core +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
An Energy-Efficient Self-Organization Routing Strategy in Tree Networks
EAI Endorsed Transactions on Energy Web, 2015 This paper proposes a new self-organization and topology dynamic adjustment strategy. Network nodes broadcast packets to select child nodes and non-network nodes collect packets to join in network.
Lin Feng, Yu Zhou, Tie Qiu
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Financial due diligence analysis of business operations of a branch of one domestic enterprise [PDF]
Ekonomija: teorija i praksa, 2020 For the purpose of writing this paper, a financial analysis known as "due diligence" was carried out in a branch of one domestic company (hereinafter referred to as the Branch) for the period 2012-2017.
Filipović Luka +2 more
doaj
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source