Optimal management of Cogan’s syndrome: a multidisciplinary approach [PDF]
Cogan's syndrome (CS) is a rare disorder characterized by nonsyphilitic interstitial keratitis (IK) and audio-vestibular symptoms. CS affects mainly young Caucasian adults, mostly during their first three decades of age, and may develop into typical and ...
D'Aguanno, Vittorio +3 more
core +1 more source
Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu +6 more
wiley +1 more source
BRAF- and MEK-targeted small molecule inhibitors exert enhanced antimelanoma effects in combination with oncolytic reovirus through ER stress [PDF]
Reovirus type 3 (Dearing) (RT3D) infection is selective for cells harboring a mutated/activated RAS pathway. Therefore, in a panel of melanoma cell lines (including RAS mutant, BRAF mutant and RAS/BRAF wild-type), we assessed therapeutic combinations ...
Aadil A Khan +52 more
core +1 more source
Influence of tumors on protective anti-tumor immunity and the effects of irradiation [PDF]
Innate and adaptive immunity play important roles in the development and progression of cancer and it is becoming apparent that tumours can influence the induction of potentially protective responses in a number of ways.
Alan Graham Pockley +6 more
core +2 more sources
Transcriptome Signature of Immune Cells Post Reovirus Treatment in KRAS Mutated Colorectal Cancer
Elisha J Fogel,1 Avishai Samouha,1 Sanjay Goel,2 Radhashree Maitra1,2 1Department of Biology, Yeshiva University, New York, NY, 10033, USA; 2Albert Einstein College of Medicine at Montefiore Medical Center, Bronx, NY, 10461, USACorrespondence: Radhashree
Fogel EJ, Samouha A, Goel S, Maitra R
doaj
Reovirus is a double-stranded RNA virus with demonstrated oncolysis or preferential replication in cancer cells. The oncolytic properties of reovirus appear to be dependent, in part, on activated Ras signaling.
J. Gong, Esha Sachdev, A. Mita, M. Mita
semanticscholar +1 more source
Study of the murine viruses present in 'germfree' mice Final report, 1 Sep. 1968 - 30 Jun. 1970 [PDF]
Murine viruses in germfree mice selected for extraterrestrial life testing of Apollo lunar ...
Parker, J. C.
core +1 more source
Pathogens associated with acute infectious canine tracheobronchitis in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Masters in Veterinary Studies in Virology at Massey University, Turitea, Palmerston North, New Zealand [PDF]
Infectious canine tracheobronchitis (ICT) or canine infectious respiratory disease, commonly known as kennel cough, is an acute, highly contagious respiratory disease that affects the larynx, trachea, bronchi, and occasionally the parenchyma of the lower
Sowman, Harriett Rose
core
The impact of hypoxia on oncolytic virotherapy [PDF]
The hypoxic tumor microenvironment plays significant roles in tumor cell metabolism and survival, tumor growth, and progression. Hypoxia modulates target genes in target cells mainly through an oxygen-sensing signaling pathway mediated by hypoxia ...
Sheng Guo, Z
core +3 more sources
Biocidal effects of silver Final technical report [PDF]
Elimination of microbial and viral agents from spacecraft water systems by silver ions from electrolytic ion ...
Cliver, D. O. +2 more
core +1 more source

