Results 201 to 210 of about 25,961 (244)
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Reoxygenation and rehypoxiation in the SCCVII mouse tumor
International Journal of Radiation Oncology*Biology*Physics, 1994To test the hypothesis that, following preferential killing of tumor hypoxic cells, the fraction of hypoxic cells in the tumor will reestablish itself to pretreatment levels (rehypoxiation) with the same kinetics as for reoxygenation.Mouse squamous cell carcinoma VII (SCCVII) tumors were treated with a single dose of 10 Gy or a single dose of the ...
I H, Kim, J M, Brown
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Reoxygenation-induced rigor-type contracture
Journal of Molecular and Cellular Cardiology, 2003The hypothesis tested was that reoxygenation-induced contracture of myocardial cells, a form of reperfusion injury, can be due to a rigor-type mechanism. Isolated adult cardiomyocytes were exposed to 30- or 60-min anoxia (pH 6.4) and reoxygenation (pH 7.4). In cardiomyocytes, cytosolic Ca(2+) and cell length, and in isolated rat hearts left ventricular
Yury, Ladilov +8 more
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Sodium pump failure in hypoxia and reoxygenation
Journal of Molecular and Cellular Cardiology, 1992Sodium pump measurements have not been previously documented in the intact heart close to the onset of irreversible injury in hypoxia and reoxygenation. In the present experiments, Rb+ uptake was measured in the presence and absence of ouabain in Langendorff-perfused rat hearts. In the presence of ouabain, Rb+ uptake was increased after 10 min hypoxia (
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Reoxygenation of Tumors During Fractionated Radiotherapy
Radiology, 1969The work on dose-response of mammalian cells in tissue culture under oxygenated and under anoxic conditions led to calculations of the dose required to cure human tumors. It was immediately apparent that much larger doses would be needed than are used clinically.
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Reoxygenation of hypoxic tumour cells.
Strahlentherapie, 1977The present status of our knowledge on the reoxygenation of hypoxic tumour cell during fractionated radiotherapy is reviewed. The phenomenon of reoxygenation does not eliminate the need for studies of hypoxic sensitizers or high LET radiation.
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Hypoxia and reoxygenation in human melanoma xenografts
International Journal of Radiation Oncology*Biology*Physics, 1989Tumor hypoxia and reoxygenation pattern following single dose (10.0 Gy) and fractionated (7 fractions of 2.0 Gy, 1 fraction per day) irradiation were studied in five human melanoma xenograft lines using the paired survival curve method. The hypoxic fractions differed significantly among the melanoma lines; they were found to be 6 +/- 3% (E.E.), 22 ...
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[Ultrastructural changes in myocardial anoxia and reoxygenation].
Bollettino della Societa italiana di biologia sperimentale, 1982The aim of this study is to describe the ultrastructural changes in anoxic rat hearts perfused with Langendorff technique and the effects of reoxygenation on myocardial cells. After 1 h of aerobic perfusion, the hearts were subjected to 30 min of anoxia and then to 5 and 30 min of reoxygenation.
Bugiardini R. +4 more
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Zhonghua yi xue za zhi, 2005
To investigate the role of graded reoxygenation with cardiopulmonary bypass (CPB) in prevention of reoxygenation injury in children with cyanotic congenital heart defects, and to evaluate its safety.Twenty pediatric patients with cyanotic congenital heart defect were randomly divided into 2 equal groups according to CPB methodology: group 1, undergoing
Zhong-qun, Zhu +5 more
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To investigate the role of graded reoxygenation with cardiopulmonary bypass (CPB) in prevention of reoxygenation injury in children with cyanotic congenital heart defects, and to evaluate its safety.Twenty pediatric patients with cyanotic congenital heart defect were randomly divided into 2 equal groups according to CPB methodology: group 1, undergoing
Zhong-qun, Zhu +5 more
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