Results 91 to 100 of about 3,010,841 (282)
, 2016 We study the performance of Reed-Solomon (RS) codes for the \em exact repair problem \em in distributed storage. Our main result is that, in some parameter regimes, Reed-Solomon codes are optimal regenerating codes, among MDS codes with linear repair ...
Guruswami, Venkatesan, Wootters, Mary
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Bioelectronic MedicineCervical spinal cord injury (SCI) impairs sensorimotor and autonomic functions. We investigated the effects of lumbosacral transcutaneous spinal cord stimulation (tSCS) on urinary bladder, bowel, and sexual function as well as cardiovascular and ...
Soshi Samejima +15 more
doaj +1 more source
Repair Locality From a Combinatorial Perspective
, 2014 Repair locality is a desirable property for erasure codes in distributed storage systems. Recently, different structures of local repair groups have been proposed in the definitions of repair locality.
Wang, Anyu, Zhang, Zhifang
core +1 more source
Knee Surgery & Related Research, 2014 The meniscus has several important roles, such as transmission of the load, absorption of the shock in the knee joint, acting as a secondary anteroposterior stabilizer of the knee joint, and contributing to proprioception of the knee joint. Degenerative changes of the knee joint develop in the long-term follow-up even after partial meniscectomy.
Yoon, Kyoung Ho, Park, Keun Ho
openaire +3 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Privacy Vulnerabilities in the Practices of Repairing Broken Digital Artifacts in Bangladesh [PDF]
, 2017 This paper presents a study on the privacy concerns associated with the practice of repairing broken digital objects in Bangladesh. Historically, repair of old or broken technologies has received less attention in ICTD scholarship than design ...
Ahmed, syed Ishtiaque +4 more
core +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
On the Existence of Optimal Exact-Repair MDS Codes for Distributed Storage [PDF]
, 2010 The high repair cost of (n,k) Maximum Distance Separable (MDS) erasure codes has recently motivated a new class of codes, called Regenerating Codes, that optimally trade off storage cost for repair bandwidth.
Changho Suh +3 more
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source