Results 71 to 80 of about 3,036,040 (301)

Feasibility study on pre or postoperative accelerated radiotherapy (POP-ART) in breast cancer patients

open access: yesPilot and Feasibility Studies, 2020
Background In early-stage breast cancer, the cornerstone of treatment is surgery. After breast-conserving surgery, adjuvant radiotherapy has shown to improve locoregional control and overall survival rates.
Hans Van Hulle   +13 more
doaj   +1 more source

The Error and Repair Catastrophes: A Two-Dimensional Phase Diagram in the Quasispecies Model

open access: yes, 2003
This paper develops a two gene, single fitness peak model for determining the equilibrium distribution of genotypes in a unicellular population which is capable of genetic damage repair.
A. Giraud   +29 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Repair Matters [PDF]

open access: yes, 2016
Repair has visibly come to the fore in recent academic and policy debates, to the point that 'repair studies' is now emerging as a novel focus of research. Through the lens of repair, scholars with diverse backgrounds are coming together to rethink our relationships with the human-made matters, tools and objects that are the material mesh in which ...
Graziano, Valeria, Trogal, Kim
openaire   +1 more source

Intellectual Property Law and the Right to Repair [PDF]

open access: yes, 2019
This Article posits that intellectual property law should accommodate consumers’ right to repair their products. In recent years, there has been a growing push towards state legislation that would provide consumers with a “right to repair” their products.
Grinvald, Leah Chan, Tur-Sinai, Ofer
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Squamous Cell Carcinoma of the Bulbar Urethra Accompanied by Lichen Sclerosus: A Case Report

open access: yesAmerican Journal of Men's Health, 2018
Squamous cell carcinoma (SCC) of the bulbar urethra accompanied by lichen sclerosus (LS) is rarely reported. This study reports the case of a 56-year-old man with urethral squamous cell carcinoma (USCC) accompanied by a long history of genital LS.
Xufeng Peng   +4 more
doaj   +1 more source

Locally Repairable Codes with Multiple Repair Alternatives

open access: yes, 2013
Distributed storage systems need to store data redundantly in order to provide some fault-tolerance and guarantee system reliability. Different coding techniques have been proposed to provide the required redundancy more efficiently than traditional ...
Hollmann, Henk D. L.   +2 more
core   +1 more source

Do Outcomes of Arthroscopic Subscapularis Tendon Repairs Depend on Rotator Cuff Fatty Infiltration? [PDF]

open access: yes, 2020
Background:Rotator cuff fatty infiltration has been correlated with poorer radiographic and clinical outcomes in supraspinatus and infraspinatus tendon repairs, but this has not been well-studied in subscapularis tendon repairs.
Feeley, Brian T   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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