Results 91 to 100 of about 3,036,040 (301)
Stem cell therapy for neurological disorders: A focus on aging
Neurobiology of Disease, 2019 Age-related neurological disorders continue to pose a significant societal and economic burden. Aging is a complex phenomenon that affects many aspects of the human body.
Hung Nguyen +8 more
doaj +1 more source
Privacy Vulnerabilities in the Practices of Repairing Broken Digital Artifacts in Bangladesh [PDF]
, 2017 This paper presents a study on the privacy concerns associated with the practice of repairing broken digital objects in Bangladesh. Historically, repair of old or broken technologies has received less attention in ICTD scholarship than design ...
Ahmed, syed Ishtiaque +4 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Bioelectronic MedicineCervical spinal cord injury (SCI) impairs sensorimotor and autonomic functions. We investigated the effects of lumbosacral transcutaneous spinal cord stimulation (tSCS) on urinary bladder, bowel, and sexual function as well as cardiovascular and ...
Soshi Samejima +15 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Bone Marrow-Derived Stem Cell Therapy for Metastatic Brain Cancers
Cell Transplantation, 2015 We propose that stem cell therapy may be a potent treatment for metastatic melanoma in the brain. Here we discuss the key role of a leaky blood-brain barrier (BBB) that accompanies the development of brain metastases.
Yuji Kaneko +9 more
doaj +1 more source
An Explicit Construction of Systematic MDS Codes with Small Sub-packetization for All-Node Repair
, 2018 An explicit construction of systematic MDS codes, called HashTag+ codes, with arbitrary sub-packetization level for all-node repair is proposed. It is shown that even for small sub-packetization levels, HashTag+ codes achieve the optimal MSR point for ...
Gligoroski, Danilo, Kralevska, Katina
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Knee Surgery & Related Research, 2014 The meniscus has several important roles, such as transmission of the load, absorption of the shock in the knee joint, acting as a secondary anteroposterior stabilizer of the knee joint, and contributing to proprioception of the knee joint. Degenerative changes of the knee joint develop in the long-term follow-up even after partial meniscectomy.
Yoon, Kyoung Ho, Park, Keun Ho
openaire +3 more sources