Results 131 to 140 of about 1,567,787 (319)

Unifying Self- and Other-Repair [PDF]

, 2007
Ginzburg J, Fernández R, Schlangen D. Unifying Self- and Other-Repair. In: Proceeding of DECALOG, the 11th International Workshop on the Semantics and Pragmatics of Dialogue (SemDial07).
Fernández, Raquel, Ginzburg, Jonathan, Schlangen, David ; https://orcid.org/   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Melatonin as an Antioxidant for Stroke Neuroprotection

Cell Transplantation, 2016
Melatonin ( N -acetyl-5-methoxytryptamine) is a hormone derived from the pineal gland that has a wide range of clinical applications. While melatonin was originally assessed as a hormone specializing in regulation of the normal circadian rhythm in ...
Nate Watson, Theo Diamandis, Chiara Gonzales-Portillo, Stephanny Reyes, Cesar V. Borlongan Ph.D.   +4 more
doaj   +1 more source

Characterisation of XPD from Sulfolobus acidocaldarius : an iron-sulphur cluster containing DNA repair helicase [PDF]

, 2007
DNA is constantly damaged by a variety of exogenous and endogenous sources. To maintain the integrity of the genome, different DNA repair mechanisms have evolved, which deal with different kinds of DNA damage.
Rudolf, Jana
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

CIRCULATING MYELOID-DERIVED SUPPRESSOR CELLS AS A POTENTIAL BIOINDICATOR OF THE ENDOGENOUS MYELIN REPAIR CAPACITY IN EXPERIMENTAL MULTIPLE SCLEROSIS

IBRO Neuroscience Reports, 2023
Mari Paz Serrano-Regal, Inmaculada Alonso-García, Celia Camacho-Toledano, Isabel Machin-Diaz, María Cristina Ortega, Leticia Calahorra, Diego Clemente   +6 more
doaj   +1 more source

Significance of the concentration of chloride in the repair of concrete highway structures using surface applied corrosion inhibitors [PDF]

, 2005
Presented at the first International Conference on Concrete Repair, Rehabilitation and Retrofitting (ICCRRR 2005), Cape Town, South Africa, 21-23 November, 2005Advances in surface-applied corrosion inhibitors suggest that they have the potential to ...
Richardson, Mark G., Grimes, E., Söylev, T. A., McNally, Ciaran   +3 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Impact of weightbearing on progressive collapsing foot deformity shape: a geometric morphometric analysis

Bone & Joint Open
Aims: Weightbearing CT (WBCT) has set a new standard for the assessment of foot and ankle alignment in patients with progressive collapsing foot deformity (PCFD) under physiological loading conditions compared with conventional CT.
Jing Li, Cédric Bonte, Emmanuel Audenaert, Arne Burssens, Matthias Peiffer, Ide Van den Borre, Roel Huysentruyt, Aline Van Oevelen, Kate Duquesne   +8 more
doaj   +1 more source