Results 41 to 50 of about 3,036,040 (301)

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Adipose Tissue–Derived Exosomes as a Novel Therapeutic Approach for Refractory Alopecia Areata: A Report of Two Cases

Case Reports in Dermatological Medicine
Alopecia areata (AA) is an autoimmune condition with unpredictable progression, negatively impacting the quality of life. Despite various therapeutic options, refractory cases remain challenging to treat. Emerging evidence highlights the regenerative and
Mohammad Ali Nilforoushzadeh, Nazila Heidari, Amirhossein Heidari, Niloufar Najar Nobari   +3 more
doaj   +1 more source

Hippocampal interneuronal dysfunction and hyperexcitability in a porcine model of concussion

Communications Biology, 2023
Cognitive impairment is a common symptom following mild traumatic brain injury (mTBI or concussion) and can persist for years in some individuals.
Alexandra V. Ulyanova, Christopher D. Adam, Carlo Cottone, Nikhil Maheshwari, Michael R. Grovola, Oceane E. Fruchet, Jami Alamar, Paul F. Koch, Victoria E. Johnson, D. Kacy Cullen, John A. Wolf   +10 more
doaj   +1 more source

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim, Natalie Bradford, David Brain, Sameera Senanayake, Sanjeewa Kularatna, Kate Young, Christine Cashion, Tim Hassall, Susanna Cramb   +8 more
wiley   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

The Mechanistic Role of PPARγ in Wound Healing

PPAR Research
The receptor known as peroxisome proliferator-activated receptor gamma (PPARγ) is crucial for effective wound healing, and recent progress has given a deeper understanding of its complex functions.
Zhaojun Wang, Kaixing Jia, Wei Wang, Xiaolong Du, Yueyan Wu, Jianan Wang   +5 more
doaj   +1 more source

Effect of DNA repair deficiencies on the cytotoxicity of resveratrol [PDF]

, 2015
Numerous preclinical studies have shown that the naturally-occurring polyphenol resveratrol may produce health-beneficial effects in a variety of disorders, including cancer, diabetes, Alzheimer, and cardiovascular diseases.
Burgos Morón, Estefanía, Calderón Montaño, José Manuel, López Lázaro, Miguel, López Lázaro, Miguel (Coordinador), Mateos Cordero, Santiago, Orta Vázquez, Manuel Luis   +5 more
core  

Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada, Makoto Harada, Tadahiko Kikugawa, Takeshi Nakata, Koji Hashimoto, Tsuneo Konta, Yuji Kamijo   +6 more
wiley   +1 more source

Regenerative Potential of Adipose Tissue–Derived Exosomes in Treating Hair Shaft Abnormalities: A Case Report

Case Reports in Dermatological Medicine
Hair shaft abnormalities, often linked to genetic or acquired conditions, present significant treatment challenges with limited and inconsistent therapeutic success.
Mohammad Ali Nilforoushzadeh, Amirhossein Heidari, Nazila Heidari, Niloufar Najar Nobari   +3 more
doaj   +1 more source

Skilled reaching deterioration contralateral to cervical hemicontusion in rats is reversed by pregabalin treatment conditional upon its early administration

PAIN Reports, 2019
. Introduction:. Gabapentinoids are first-line treatments for painful traumatic and nontraumatic central nervous system disorders. Evidence from a large human study suggests that early use of gabapentinoids after spinal cord injury improves motor scores.
Erin L.K.S. Erskine, Brittney D. Smaila, Ward Plunet, Jie Liu, Elizabeth E. Raffaele, Wolfram Tetzlaff, John L.K. Kramer, Matt S. Ramer   +7 more
doaj   +1 more source