Results 81 to 90 of about 251,710 (258)

CRISPR-edited human ES-derived oligodendrocyte progenitor cells improve remyelination in rodents

Nature Communications
In Multiple Sclerosis (MS), inflammatory demyelinated lesions in the brain and spinal cord lead to neurodegeneration and progressive disability. Remyelination can restore fast saltatory conduction and neuroprotection but is inefficient in MS especially ...
Laura J. Wagstaff, Nadine Bestard-Cuche, Maja Kaczmarek, Antonella Fidanza, Lorraine McNeil, Robin J. M. Franklin, Anna C. Williams   +6 more
doaj   +1 more source

An Explicit Constitutive Reconstruction Framework for Mechanical Characterization of Miniaturized 3D‐Printed Specimens

Advanced Engineering Materials, EarlyView.
An explicit constitutive reconstruction framework enables accurate tensile characterization of miniaturized additively manufactured specimens using only the grip‐to‐grip displacement measurements. Progressive validation through self‐consistency, analytical comparison, and inverse finite element method (iFEM) benchmarking demonstrates constitutive ...
Junqing Leng, Caralyn Collins, Pengpeng Zhang, Joanna Zhang, Cheng Sun   +4 more
wiley   +1 more source

Cell and tissue patterning starfish arm regeneration: a microscopic overview

, 2016
Purpose: to provide a comprehensive overview of cell and tissue patterning of starfish regenerative processes Methods: Two ecologically different starfish species (Marthasterias glacialis and Echinaster sepositus) were subjected to traumatic arm tip ...
M.D. Candia Carnevali, A. Daviddi, C. Ferrario, Y. B. Khadra, M. Sugni, F. Bonasoro   +5 more
core   +2 more sources

HUMAN MESENCHYMAL STEM CELLS AS A MODEL OF STUDY FOR NEW BIOMATERIALS IN BONE TISSUE REGENERATION [PDF]

, 2012
The reconstruction of large bone segments remains a critical clinical problem in the case of extensive bone loss due to traumatic or pathological events. Due to its ideal biocompatibility and osteogenic properties, autologous bone is still considered the
Manfrini, Marco
core  

Growth factor interactions in bone regeneration [PDF]

, 2010
Growth factor interactions in bone regeneration. Diederik H R Kempen, Laura B Creemers, Jacqueline Alblas, Lichun Lu, Abraham J Verbout, Michael J Yaszemski and Wouter J A Dhert 1 Department of Orthopedics, University Medical Center , Utrecht, The ...
Creemers, L.B., Tissue Repair, Yaszemski, M.J., Michael J. Yaszemski, Kempen, D.H.R., Lu, L., Wouter J.A. Dhert, Diederik H.R. Kempen, Geneeskunde van gezelschapsdieren, Laura B. Creemers, Alblas, J., Verbout, A.J., Dhert, W.J.A., Abraham J. Verbout, Jacqueline Alblas, Lichun Lu   +15 more
core   +1 more source

Adaptive Foam 3D Printing of Ultralight and Multifunctional Materials

Advanced Engineering Materials, EarlyView.
Adaptive foam 3D printing, enabled by expandable microspheres, imparts cellular structures to thermoplastic and thermosetting polymers, manufactured through a variety of processes including fused filament fabrication, direct ink writing, digital light processing, and inkjet printing.
Nariman Rajabifar, Amir Ameli
wiley   +1 more source

Effects of sleep deprivation on cognition and synaptic associated proteins in rodents: A systematic review and meta-analysis

Journal of Alzheimer's Disease Reports
Background Sleep disorders are a significant risk factor for cognitive decline and Alzheimer's disease (AD). However, preclinical studies investigating the effects of sleep deprivation (SD) on cognition and synaptic proteins have produced inconsistent ...
Hongqi Wang, Xin Mao, Siyu Liu, Jiacheng Zhang, Enze Li, Yizhi Song, Hui Li, Lirong Chang, Yan Wu   +8 more
doaj   +1 more source

Morphology, Transport, and Dynamics of Protein Adsorption in Open‐Cell Metal Foam

Advanced Engineering Materials, EarlyView.
Stainless steel (SS) open‐cell foams are shown to adsorb more protein per unit area than previously reported 316L SS and chromium oxide surfaces under static and flow conditions. An integrated approach combining 3D pore imaging, flow simulation, and protein adsorption experiments characterizes the foam’s performance.
Chinmaya Prerana Inguva, Joseph Lavoie, Afsaneh Rabiei   +2 more
wiley   +1 more source

The scale-up of a tissue engineered porous hydroxyapatite polymer composite scaffold for use in bone repair: an ovine femoral condyle defect study

, 2014
The development of an osteogenic bone graft substitute has important practical and cost implications in many branches of medicine where bone regeneration is required.
Oreffo, Richard O. C., Purcell, Matthew, Tayton, Edward, Dunlop, Douglas G., Shakesheff, Kevin M., Goodship, Allen, Fowler, Darren, Smith, James O., Howdle, Steven M., Oreffo, Richard O.C., Blunn, Gordon, Lanham, Stuart, Tayton, Edward R.   +12 more
core   +1 more source

3D‐Printed Titanium Gyroid Scaffold Structure Integrated With Tough Hybrid Materials for Cartilage Replacement

Advanced Engineering Materials, EarlyView.
This study proposes a potential device design for joint cartilage replacement. Silica‐polytetrahydrofuran (SiO2‐PolyTHF) hybrids with customizable mechanical properties were developed to mimic the characteristics of a natural meniscus. These were synthesized through a two‐pot sol–gel hybrid process.
Yu‐Chien Lin, Gloria R. Young, Francesca Tallia, Reece N. Oosterbeek, Shaaz Ghouse, Edward Spiers, Nupur Kohli, Tom Briggs, Marc Masen, Siwei Li, Ren‐Jei Chung, Jonathan R. T. Jeffers, Julian R. Jones   +12 more
wiley   +1 more source