Results 91 to 100 of about 17,320 (252)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

A Policy Platform to Deliver Black Reparations: Building on Evidence from Child Development Accounts

open access: yesRSF: The Russell Sage Foundation Journal of the Social Sciences
Successful Black reparations require a policy for delivering payments, one that provides for effective identification, disbursement, asset protection, and asset growth over time.
Trina R. Shanks   +5 more
doaj   +1 more source

Los Angeles Community Coalitions on Redress/Reparations

open access: yes, 1979
Meeting minutes for the Los Angeles Communtiy Coalition on Redress/Reparations (LACCRR). Minutes include: "Outreach," "Conference," "Media Presentation," "Treasurer's Report," "Announcements," and "Other Businesses."The Jim Matsuoka Nikkei for Civil ...
Los Angeles Community Coalition on Redress/Reparations;
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

New redress bills: what will it take to win reparations?

open access: yes, 1985
Flyer for an event sponsored by the National Coalition for Redress/Reparations (NCRR) held at the Little Tokyo Towers. Program includes: "Update on Bills," "What can we do?," and ""Cold Tofu" Improvisational Comedy Group."The Jim Matsuoka Nikkei for ...
National Coalition for Redress/Reparations (U.S.)
core   +1 more source

The Politics of Expedience: Evanston, Illinois, and the Fight for Reparations

open access: yesRSF: The Russell Sage Foundation Journal of the Social Sciences
In March 2021, the city council in Evanston, Illinois, began distributing reparations funds to Black residents in the form of $25,000 housing grants. In doing so, Evanston became the first city in the United States to provide publicly funded reparations ...
Monique Newton, Matthew D. Nelsen
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

National Coalition for Redress/Reparations

open access: yes
Flyer from the National Coalition for Redress/Reparations (NCRR) calling for justice and reparations. A handwritten note on the right side reads CSULB.The Jim Matsuoka Nikkei for Civil Rights and Redress Collection includes brochures, meeting notes and ...
National Coalition for Redress/Reparations (U.S.)
core  

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