Results 81 to 90 of about 17,320 (252)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

National Coalition for Redress/Reparations (NCRR)

, 1998
Brochure for the National Coalition for Redress/Reparations (NCRR) with a list of 1998 Los Angeles Chapter officers and board of directors.The Jim Matsuoka Nikkei for Civil Rights and Redress Collection includes brochures, meeting notes and agendas ...
National Coalition for Redress/Reparations (U.S.)
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

National Coalition for Redress and Reparations

Leaflet for the National Coalition for Redress/Reparations (NCRR). Topics include: "Background to the Redress/Reparations Issue" and "Future Plans."The Jim Matsuoka Nikkei for Civil Rights and Redress Collection includes brochures, meeting notes and ...
National Coalition for Redress/Reparations (U.S.): publisher
core   +1 more source

National conference for justice now! Reparations now!

, 1980
Event flyer and schedule for the National Conference for Justice now! Reparations now! event at California State University, Los Angeles. Schedule includes a list of educational workshops, speakers, and participants.The Jim Matsuoka Nikkei for Civil ...
National Coalition for Redress/Reparations (U.S.)
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Sotakorvaukset ja Suomen toivottu tulevaisuus 1945-52

Ennen ja Nyt: Historian Tietosanomat
Suomen maakuva sisältää elementtejä luonnosta sekä tasa-arvoisesta yhteiskunnasta, jossa elää on-nellinen kansakunta. Sen perusvire on säilynyt lähes muuttumattomana toisen maailmansodan jälkei-sinä vuosikymmeninä.
Karl-Erik Michelsen
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

National Coalition for Redress/Reparations

, 1980
Flyer published by the National Coalition for Redress/Reparations, which has been named as the Nikkei for Civil Rights and Redress (NCRR) since 2000, with information about the principles and goals of the organization.The Roy Nakano Nikkei for Civil ...
National Coalition for Redress/Reparations (U.S.): publisher
core  

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source