Results 141 to 150 of about 1,043,057 (388)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Review: Resolving the Fine Structure in the Energy Landscapes of Repeat Proteins — R0/PR1
, 2022 Benjamin S. Hanson
openalex +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Position Measurements Obeying Momentum Conservation
, 2011 We present a hitherto unknown fundamental limitation to a basic measurement: that of the position of a quantum object when the total momentum of the object and apparatus is conserved.
H. Stein +4 more
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Genetic diversity and population structure of Ethiopian finger millet (Eleusine coracana (L.) Gaertn) genotypes using inter simple sequence repeat (ISSR) markers [PDF]
, 2017 Brhane Haftom +2 more
openalex +1 more source
Repeatability, accuracy, portability, and errors of the portable alignment gyrocompass system [PDF]
Portable alignment gyrocompass system accuracy, repeatability, portability, and ...
Mihm, J. J., Murphy, R. A.
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Repeatability of the subjective refraction [PDF]
, 2017 Actualment, l’error refractiu és considerat un problema de salut a nivell mundial. Un examen refractiu precís és vital per obtenir la millor agudesa visual possible i portar a terme correctament altres exàmens visuals.
Vázquez López, Meritxell
core
Agreement between two successive transvaginal salpingosonography assessments of tubal patency
Acta Obstetricia et Gynecologica Scandinavica, 1997 Objective. To evaluate the agreement between repeat transvaginal sonographic assessments of tubal patency using a combination of air and saline. Material and methods. Twenty‐nine patients were examined twice by the same investigator (H.S.).
Aydin Tekay +3 more
doaj +1 more source