Results 41 to 50 of about 1,652,346 (296)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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An experimental investigation of cyclically, axially loaded piles in sand [PDF]
, 1993 Bibliography: leaves 91-93.The research work involved the installation and cyclic load testing of large-scale pressure-grouted, instrumented piles in sand in the laboratory.
Cowburn, S J
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Hydromechanical behavior of unsaturated expansive clay under repetitive loading
Journal of Rock Mechanics and Geotechnical Engineering, 2021 Compacted layers of expansive soils are used in different engineering projects, such as subgrades, engineered clay barriers, and buffers for radioactive waste disposal. These layers are exposed to a variety of stresses and wetting conditions during field
Ahmed M. Al-Mahbashi +2 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Journal of Engineering and Sustainable Development, 2017 This research is an experimental study to evaluate the effect of lap splice of high-strength steel bars in reactive powder concrete beams exposed to repeated loading.
Hisham M Al-Hassani +2 more
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SensorsReinforced Concrete (RC) structures experience progressive degradation over their service life due to mechanical loading and environmental exposure, leading to reduced bearing capacity and compromised structural safety. Incorporating discrete fibers into
George M. Sapidis +6 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Failure mode for SS400 notched specimen under repeated impact loading
Nihon Kikai Gakkai ronbunshu, 2019 We conducted impact fatigue tests, wherein the magnitude and duration times of impact stresses were varied for JIS SS400 notched specimens to evaluate the effect of strain amplitudes on the impact fatigue strength.
Hiroaki HASHIMOTO +4 more
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