Results 61 to 70 of about 3,681,265 (301)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Optimal two-treatment repeated measurement designs for two periods

, 2008
Repeated measurement designs, with t = 2 treatments, n (experimental) units, and p = 2 periods are examined. The parameters of interest are the difference of direct treatment effects and the difference of residual effects.
Kounias, Stratis, Chalikias, Miltiadis
core   +1 more source

Numerical and experimental analysis of a novel passive feedback valve for variable fluid volume metering in centrifugal microfluidic platforms

Materials & Design
In lab-on-a-disc systems, operations that involve repeated reagent handling demand the integration of repeatable valves and a suitable metering unit operation.
Amirhossein Saboorinia, Amirhosein Ghasemi, Abas Ramiar   +2 more
doaj   +1 more source

HE Plots for Repeated Measures Designs [PDF]

Hypothesis error (HE) plots, introduced in Friendly (2007), provide graphical methods to visualize hypothesis tests in multivariate linear models, by displaying hypothesis and error covariation as ellipsoids and providing visual representations of effect
Michael Friendly
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

An uncertainty-aware framework for solid-phase measurement and verification of enhanced weathering

Frontiers in Climate
Reliable verification of enhanced weathering as a carbon dioxide removal strategy requires accurate quantification of feedstock dissolution in amended soils.
Brian Rogers, Kate Maher
doaj   +1 more source

The Design and Development of Sit to Stand Trainer for the Elderly

Walailak Journal of Science and Technology, 2020
Strengthening exercise for lower limbs is required in elderly. Repeated sit to stands could improve lower limbs strength, reduce limitations, and fall. The researchers developed a Sit to Stand Trainer, a device that assists and offers variable levels of
Sairag SA-ADPRAI, Bunyong RUNGROUNGDOUYBOON   +1 more
doaj   +1 more source

The Analysis of Very Small Samples of Repeated Measurements [PDF]

The statistical analysis of repeated measures or longitudinal data always requires the accommodation of the covariance structure of the repeated measurements at some stage in the analysis.
Skene, Simon Scott
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Optimal designs for indirect regression [PDF]

, 2004
In many real life applications, it is impossible to observe the feature of interest directly. For example, scientists in Materials Science may be interested in detecting cracks inside objects, not visible from the outside. Similarly, non-invasive medical
Edmund Jones, G. Vitale, Osses Alvarado, Axel, Nicolai Bissantz, Vitale, Guido, Cumsille, Patricio, Takahashi, Takéo, Hajo Holzmann, Chern, I-Liang, Conca, Carlos, Preziosi, Luigi, Kavian, O., L. Preziosi, Zuo, D., Langer, Matthias, Censor, Yair, Mueller, J. L., Ambrosi, Davide Carlo, Malik, Muslim, Schwindt, Erica L., Anthony Dubois, Herrera, C. N. L., Bissantz, Nicolai, Hamilton, S. J., Horng-Shing Lu, Henry, Pierro, Álvaro Rodolfo De, Schwindt, Erica, Rosier, Lionel, Helou Neto, Elias Salomão, Muslim Malik, Marc Saillard, Cheney, Margaret, Jiang, Ming, Kawano, Alexandre, Kamal Belkebir, Dette, Holger, Alvarez, Catalina, Von Herrmann, A., Holger Dette, Monard, F., Margaret Cheney, Holzmann, Hajo, Courdurier Bettancourt, Matías, Borden, Brett, Friz, L., Pandolfi, Luciano, Chen, Tai-Been, Romero, F., Brett Borden, Stefanie Biedermann, Conca Rosende, Carlos, Munnier, Alexandre, Ortega Palma, Jaime, Jones, Edmund, Woracek, Harald, Carlos Conca, Biedermann, Stefanie, Hamilton, Sarah J., Alexandre Munnier   +58 more
core   +1 more source